1887

Abstract

Hantavirus infections are emerging zoonoses. In Asia, the hantavirus commonly manifests as haemorrhagic fever with renal syndrome (HFRS), apparent with fever, thrombocytopenia and acute kidney injury. There are a few cases with the atypical clinical course with cardiopulmonary symptoms in Asia including Sri Lanka. Here, we report a case of hantavirus infection with an atypical cardiopulmonary syndrome-like illness with serological evidence of the Puumala/Puumala-like virus.

Funding
This study was supported by the:
  • Not applicable (Award Not applicable)
    • Principle Award Recipient: NotApplicable
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Loading

Article metrics loading...

/content/journal/acmi/10.1099/acmi.0.000554.v3
2024-04-12
2024-04-29
Loading full text...

Full text loading...

/deliver/fulltext/acmi/6/4/acmi000554.v3.html?itemId=/content/journal/acmi/10.1099/acmi.0.000554.v3&mimeType=html&fmt=ahah

References

  1. Jonsson CB, Figueiredo LTM, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev 2010; 23:412–441 [View Article] [PubMed]
    [Google Scholar]
  2. Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases E-Book Elsevier Health Sciences; 2019
    [Google Scholar]
  3. Muthugala R, Dheerasekara K, Manamperi A, Gunasena S, Galagoda G. Hantavirus Hemorrhagic Fever with renal syndrome - suspected cases in Sri Lanka: clinical picture and epidemiology from 2013-2021. Jpn J Infect Dis 2022; 75:533–536 [View Article] [PubMed]
    [Google Scholar]
  4. Muthugala R, Dheerasekara K, Harischandra N, Wickramasinghe D, Abeykoon M et al. Hantavirus infection with pulmonary symptoms in north central part of Sri Lanka. J Clin Virol Plus 2021; 1:100052 [View Article]
    [Google Scholar]
  5. Clinical Manifestation | Hantavirus | DHCPP | CDC; 2019 https://www.cdc.gov/hantavirus/technical/hps/clinical-manifestation.html accessed 22 May 2022
  6. Malavige GN, Jeewandara C, Ghouse A, Somathilake G, Tissera H. Changing epidemiology of dengue in Sri Lanka-challenges for the future. PLoS Negl Trop Dis 2021; 15:e0009624 [View Article] [PubMed]
    [Google Scholar]
  7. Stamm DR, Stankewicz HA. Atypical Bacterial Pneumonia,” in StatPearls, Treasure Island (FL) StatPearls Publishing; 2022
    [Google Scholar]
  8. Mendis C, Thevanesam V, Kumara A, Wickramasinghe S, Madegedara D et al. Insight into genetic diversity of Mycobacterium tuberculosis in Kandy, Sri Lanka reveals predominance of the Euro-American lineage. Int J Infect Dis 2019; 87:84–91 [View Article] [PubMed]
    [Google Scholar]
  9. Kallio-Kokko H, Vapalahti O, Lundkvist A, Vaheri A. Evaluation of Puumala virus IgG and IgM enzyme immunoassays based on recombinant baculovirus-expressed nucleocapsid protein for early nephropathia epidemica diagnosis. Clin Diagn Virol 1998; 10:83–90 [View Article] [PubMed]
    [Google Scholar]
  10. Akram SM, Mangat R, Huang B. “Hantavirus Cardiopulmonary Syndrome,” in StatPearls, Treasure Island (FL) StatPearls Publishing; 2022
    [Google Scholar]
  11. Gamage CD, Yasuda SP, Nishio S, Kularatne SA, Weerakoon K et al. Serological evidence of Thailand virus-related hantavirus infection among suspected leptospirosis patients in Kandy, Sri Lanka. Jpn J Infect Dis 2011; 64:72–75 [PubMed]
    [Google Scholar]
  12. Sulleiro E, Aznar ML, Serre-Delcor N, Salvador F, Sanchez-Montalvá A et al. Hantavirus pulmonary syndrome in traveler returning from Nepal to Spain. Emerg Infect Dis 2020; 26:150–153 [View Article] [PubMed]
    [Google Scholar]
  13. Sunil-Chandra NP, Clement J, Maes P, DE Silva HJ, VAN Esbroeck M et al. Concomitant leptospirosis-hantavirus co-infection in acute patients hospitalized in Sri Lanka: implications for a potentially worldwide underestimated problem. Epidemiol Infect 2015; 143:2081–2093 [View Article] [PubMed]
    [Google Scholar]
  14. Dalugama C, Nanayakkara M, Rathnayaka N, Medagama A. Atypical case of hantavirus infection in Sri Lanka mimicking leptospirosis: a case report. J Med Case Rep 2020; 14:71 [View Article] [PubMed]
    [Google Scholar]
  15. Ehelepola NDB, Basnayake BMLS, Sathkumara SMBY, Kaluphana KLR. Two atypical cases of Hantavirus infections from Sri Lanka. Case Rep Infect Dis 2018; 2018:4069862 [View Article] [PubMed]
    [Google Scholar]
  16. Vitarana T, Colombage G, Bandaranayake V, Lee HW. Hantavirus disease in Sri Lanka. Lancet Lond Engl 1988; 2:1263
    [Google Scholar]
  17. Specter S, Hodinka RL, Young SA, Wiedbrauk DL. Clinical Virology Manual American Society for Microbiology Press; 2009 [View Article]
    [Google Scholar]
  18. Avšič-Županc T, Saksida A, Korva M. Hantavirus infections. Clin Microbiol Infect 2019; 21S:e6–e16 [View Article] [PubMed]
    [Google Scholar]
  19. Duchin JS, Koster FT, Peters CJ, Simpson GL, Tempest B et al. Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. The Hantavirus Study Group. N Engl J Med 1994; 330:949–955 [View Article] [PubMed]
    [Google Scholar]
  20. Hantavirus cardiopulmonary syndrome - UpToDate. n.d https://www.uptodate.com/contents/hantavirus-cardiopulmonary-syndrome#H14 accessed 10 September 2022
  21. Riccò M, Peruzzi S, Ranzieri S, Magnavita N. Occupational Hantavirus infections in agricultural and forestry workers: a systematic review and metanalysis. Viruses 2021; 13:2150 [View Article] [PubMed]
    [Google Scholar]
  22. Sunil-Chandra NP, Fahlman Å, Waidyarathna S, Näslund J, Jayasundara MVML et al. Evidence of orthohantavirus and leptospira infections in small mammals in an endemic area of Gampaha district in Sri Lanka. One Health Outlook 2022; 4:17 [View Article] [PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/acmi/10.1099/acmi.0.000554.v3
Loading
/content/journal/acmi/10.1099/acmi.0.000554.v3
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error