1887

Abstract

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic continues, other previously ignored viruses must be taken into account as causes of severe acute respiratory distress, influenza-like illness and pneumonia. In this article, we report two cases of pneumonia in chronic liver disease patients where human coronavirus (HCoV) 229E was identified as the only infecting pathogen. Both the patients presented with fever, cough and respiratory distress, along with radiological findings suggestive of pneumonia. Multiplex real-time PCR for various respiratory viruses (FilmArray Respiratory Panel 2 ) detected HCoV-229E in both cases. Both cases were managed with prophylactic antibiotics, steroids and supplemental oxygen therapy, after which they recovered completely and were discharged.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
Loading

Article metrics loading...

/content/journal/acmi/10.1099/acmi.0.000311
2022-02-10
2022-05-22
Loading full text...

Full text loading...

/deliver/fulltext/acmi/4/2/acmi000311.html?itemId=/content/journal/acmi/10.1099/acmi.0.000311&mimeType=html&fmt=ahah

References

  1. Li F. Structure, function, and evolution of coronavirus spike proteins. Annu Rev Virol 2016; 3:237–261 [View Article] [PubMed]
    [Google Scholar]
  2. Bradburne AF, Bynoe ML, Tyrrell DA. Effects of a “new” human respiratory virus in volunteers. Br Med J 1967; 3:767–769 [View Article] [PubMed]
    [Google Scholar]
  3. Hamre D, Procknow JJ. A new virus isolated from the human respiratory tract. Proc Soc Exp Biol Med 1966; 121:190–193 [View Article] [PubMed]
    [Google Scholar]
  4. Pene F, Merlat A, Vabret A, Rozenberg F, Buzyn A et al. Coronavirus 229E-related pneumonia in immunocompromised patients. Clin Infect Dis 2003; 37:929–932 [View Article] [PubMed]
    [Google Scholar]
  5. Folz RJ, Elkordy MA. Coronavirus pneumonia following autologous bone marrow transplantation for breast cancer. Chest 1999; 115:901–905 [View Article] [PubMed]
    [Google Scholar]
  6. Hendaus MA, Jomha FA, Alhammadi AH. Virus-induced secondary bacterial infection: a concise review. Ther Clin Risk Manag 2015; 11:1265–1271 [View Article] [PubMed]
    [Google Scholar]
  7. Thomas M, Bomar PA. Upper Respiratory Tract Infection. StatPearls [Internet] Treasure Island, FL: StatPearls Publishing; 2021 [PubMed]
    [Google Scholar]
  8. Vassilara F, Spyridaki A, Pothitos G, Deliveliotou A, Papadopoulos A. A rare case of human coronavirus 229E associated with acute respiratory distress syndrome in a healthy adult. Case Rep Infect Dis 2018; 2018:1–4 [View Article] [PubMed]
    [Google Scholar]
  9. Paules CI, Marston HD, Fauci AS. Coronavirus infections-more than just the common cold. JAMA 2020; 323:707–708 [View Article] [PubMed]
    [Google Scholar]
  10. Liu DX, Liang JQ, Fung TS. Human Coronavirus-229E, -OC43, -NL63, and -HKU1 (Coronaviridae Encyclopedia of Virology [Internet] Elsevier; 2021 pp 428–440
    [Google Scholar]
  11. Zeng Z-Q, Chen D-H, Tan W-P, Qiu S-Y, Xu D et al. Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China. Eur J Clin Microbiol Infect Dis 2018; 37:363–369 [View Article] [PubMed]
    [Google Scholar]
  12. Nicholson KG, Kent J, Hammersley V, Cancio E. Acute viral infections of upper respiratory tract in elderly people living in the community: comparative, prospective, population based study of disease burden. BMJ 1997; 315:1060–1064 [View Article] [PubMed]
    [Google Scholar]
  13. Bajpai V, Gupta E, Mitra LG, Kumar H, Maiwall R et al. Spectrum of respiratory viral infections in liver disease patients with cirrhosis admitted in critical care unit. J Lab Physicians 2019; 11:356–360 [View Article] [PubMed]
    [Google Scholar]
  14. ARDS Definition Task Force Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012; 307:2526–2533 [View Article] [PubMed]
    [Google Scholar]
  15. Sharma K, Aggarwala P, Gandhi D, Mathias A, Singh P et al. Comparative analysis of various clinical specimens in detection of SARS-CoV-2 using rRT-PCR in new and follow up cases of COVID-19 infection: Quest for the best choice. PLoS One 2021; 16:e0249408 [View Article] [PubMed]
    [Google Scholar]
  16. Dare RK, Fry AM, Chittaganpitch M, Sawanpanyalert P, Olsen SJ et al. Human coronavirus infections in rural Thailand: a comprehensive study using real-time reverse-transcription polymerase chain reaction assays. J Infect Dis 2007; 196:1321–1328 [View Article] [PubMed]
    [Google Scholar]
  17. Kwee TC, Kwee RM. Chest CT in COVID-19: what the radiologist needs to know. Radiographics 2020; 40:1848–1865 [View Article] [PubMed]
    [Google Scholar]
  18. Bellau-Pujol S, Vabret A, Legrand L, Dina J, Gouarin S et al. Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses. J Virol Methods 2005; 126:53–63 [View Article] [PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/acmi/10.1099/acmi.0.000311
Loading
/content/journal/acmi/10.1099/acmi.0.000311
Loading

Data & Media loading...

Supplements

Supplementary material 1

PDF

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error