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Volume 169, Issue 6

Biofilms as protective cocoons against biocides: from bacterial adaptation to One Health issues Open Access

Abstract

Bacteria in the food chain mostly live in communities associated with surfaces known as biofilms, which confer specific survival and adaptive abilities. In such communities, the bacteria mostly exhibit higher tolerance to external stress, and their recurrent exposure along the food chain to biocides used during cleaning and disinfection procedures raises concern about the adaptation routes they develop, both at single-cell and communal levels. In recent years, an increasing number of research subjects have focused on understanding the specific features of biofilms that enable bacterial populations to adapt to biocide exposure within a ‘protective cocoon’. The first part of this review concentrates on the diversity of adaptive strategies, including structural modulation of these biofilms, physiological response or the acquisition of genetic resistance. The second part discusses the possible side effects of biofilm adaptation to biocides on antimicrobial cross-resistance, virulence and colonization features from a One Health perspective.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): antimicrobial resistance , bacterial adaptation , biocides , biofilm , food chain and One Health
Funding
This study was supported by the:
  • Anses-INRAE doctoral fellowship
    • Principle Award Recipient: RaphaelCharron
  • Agence Nationale de la Recherche (Award ANR-21-CE35-0001)
    • Principle Award Recipient: ArnaudBridier
© 2023 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2023-06-02
2024-04-26
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/mic.0.001340
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Biofilms as protective cocoons against biocides: from bacterial adaptation to One Health issues
Microbiology 169, 001340 (2023); https://doi.org/10.1099/mic.0.001340
/content/journal/micro/10.1099/mic.0.001340
/content/journal/micro/10.1099/mic.0.001340
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