1887

Abstract

SUMMARY

Growing bacteria are sensitive to various -lactam derivatives due to their interference with peptidogly can biosynthesis. At low concentrations, penicillin G (benzylpenicillin) blocks cell division without affecting mass growth rate. The MIC for division of B/r (H266) was found to depend on the growth rate, which was modified by the nutritional conditions. Our hypothesis, that division sensitivity is proportional to the rate of peptidoglycan synthesis for septum formation, as well as to cell circumference, was thus confirmed.

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/content/journal/micro/10.1099/13500872-141-5-1081
1995-05-01
2024-04-26
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