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Summary: Arginine inhibited the competence of Bacillus subtilis growing in a chemostat at a dilution rate of 0·277 h−1. The biosynthesis of competence-stimulating activity was only partially repressed. The inhibitory effect may be due to an alteration in the cell’s capacity for being stimulated to competence and/or in its ability to take up DNA irreversibly. MnSO4 at 10−6 m restored competence immediately.
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