1887

Abstract

SUMMARY:

By gel-diffusion precipitin and antigen-absorption tests, 34 strains of PPLO ( types 1-4) were examined, and 15 antigenic components recognized. Antigens and were common to types 1, 2 and 4; was specific to type 1; was specific to type 2. Type 3 was antigenically unrelated to the remainder. Its two recognizable components were named and . Three further antigens in type 1 were recognized as 17, 39 and 40, previously defined in strains of Haemophilus and Coryne-bacterium associated with mycoplasma-like variants (Pease & Laughton, 1965); antigen 40 also occurred in type 2. Two diffusible antigens, α and β, were detected in strains of types 1 and 4; these and also were found to be shared with the bacterial strains.

All genital strains of mycoplasma isolated in this laboratory belonged to type 1, all oral strains to type 4; one rat strain belonged to type 2.

Distribution of antigenic components in strains of mycoplasma and in different strains of bacteria, including those believed to be derived from mycoplasma (or vice versa), and also in others, notably supports previous claims of relationship between types 1, 2 and 4, Corynebacterium and Haemophilus. The validity of Mycoplasma as a distinct group of micro-organisms is thus called into question.

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1965-12-01
2022-12-01
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References

  1. Brown T. McP., Nunemaker J. C. 1942; Rat-bite fever. A review of American cases with re-evaluation of etiology: report of cases. Bull. Johns Hopkins Hosp. 70:201
    [Google Scholar]
  2. Card D. H. 1959; PPLO of human genital origin ; serological classification of strains and antibody distribution in man. Br. J. vener. Dis. 35:27
    [Google Scholar]
  3. Coriell Ll, Fabrizio D. P., Wilson S. R. 1959; Comparison of PPLO strains from tissue culture by complement fixation. Ann. N. Y. Acad. Sci. 79:574
    [Google Scholar]
  4. Edward D. G. ff., Fitzgerald W. A. 1954; Inhibition of growth of pleuropneumonia-like organisms by antibody. J. Path. Bact. 68:23
    [Google Scholar]
  5. Edward D. G. ff., Freundt E. A. 1956; The classification and nomenclature of organisms of the pleuropneumonia group. J. gen. Microbiol. 14:197
    [Google Scholar]
  6. Freimer E. H., Krause R. M., McCarty M. 1959; Studies of l-forms and protoplasts of group A streptococci. I. Isolation, growth and bacteriologie characteristics. J. exp. Med. 110:853
    [Google Scholar]
  7. Huijsmans-Evers A. G. M., Ruys A. C. 1956; Microorganisms of the pleuropneumonia group (family of Mycoplasmataceae) in man. II. Serological identification and discussion of pathogenicity. Antonie van Leeuwenhoek 22:377
    [Google Scholar]
  8. Laughton N. 1954; A study of a bacterium isolated from the human cervix. J. Path. Bact. 67:169
    [Google Scholar]
  9. Lemcke R. M. 1964; A comparison of various species of Mycoplasma by gel diffusion. J. gen. Microbiol. 35:ii
    [Google Scholar]
  10. Minck R. 1953; Récherches sur l’origine des organismes du type de la péripneumonie trouvées dans les organes génitaux de la femme. C. r. hebd. Séanc. Acad. Sci., Paris 236:250
    [Google Scholar]
  11. Nicol C. S., Edward D. G. ff. 1953; Role of organisms of the pleuropneumonia group in human genital infections. Br. J. vener. Dis. 29:141
    [Google Scholar]
  12. Norman M. C, Saslaw S., Kuhn L. R. 1950; Antigenic similarity of five human strains of pleuropneumonia-like organisms. Proc. Soc. exp. Biol. Med. 75:718
    [Google Scholar]
  13. Pease P. E. 1962; Evidence that Streptobacillus moniliformis is an intermediate stage between a corynebacterium and its l-form or derived PPLO. J. gen. Microbiol. 29:91
    [Google Scholar]
  14. Pease P. E. 1963; Bacterial origin of certain viruses: identity of the Eaton agent with Streptococcus MG. Nature, Lond. 197:1132
    [Google Scholar]
  15. Pease P. E., Bisset K. A. 1962; The effect of parasitism on Gram-positive bacteria with reference to the origin of certain types of virus. Nature, Lond. 196:357
    [Google Scholar]
  16. Pease P. E., Laughton N. 1962; Observations on corynebacteria and related pleuropneumonia-like organisms (PPLO). J. gen. Microbiol. 27:383
    [Google Scholar]
  17. Pease P. E., Laughton N. 1965; The antigenic structure of Haemophilus and Corynebacterium species from the human genital tract claimed to be associated with or derived from Mycoplasma hominis. J. gen. Microbiol. 41:293
    [Google Scholar]
  18. Smith P. F., Peoples D. M., Morton H. E. 1957; Conversion of pleuropneumonia-like organisms to bacteria. Proc. Soc. exp. Biol. Med. 96:550
    [Google Scholar]
  19. Sueoka N. 1961; Variation and heterogeneity of base composition of deoxyribonucleic acids: a compilation of old and new data. J. mol. Biol. 3:31
    [Google Scholar]
  20. Taylor-Robinson D., Somerson N. L., Turner H. C., Chanock R. M. 1963; Serological relationships among human mycoplasmas as shown by complement fixation and gel diffusion. J. Bact. 85:1261
    [Google Scholar]
  21. Tourtelotte M. E., Jacobs R. E. 1959; Physiological and serological comparisons of PPLO from various sources. Ann. N.Y. Acad. Sci. 79:521
    [Google Scholar]
  22. Villemot J. M., Provost A. 1959; Récherches immunologiques sur la péripneumonie. VI. Bases d’une classification sérologique des microorganismes du genre Mycoplasma. Revue Élev. Méd. vér. Pays trop. 12:369
    [Google Scholar]
  23. Wittler R. G., Cary S. G., Lindberg R. B. 1956; Reversion of a pleuropneumonia-like organism to a corynebacterium during tissue culture passage. J. gen. Microbiol. 14:763
    [Google Scholar]
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