SUmmary: The isolation, from sheep, of strains of the Bosworth type of is recorded; it is proposed to designate this type as type E.

The toxicity of culture filtrates of type E after short growth periods is increased by treatment with crude trypsin preparations; no such increase can be demonstrated when the filtrates are from growths older than 5–7 hr. The toxin which is activated in these filtrates is the toxin iota. It appears that type E strains elaborate prototoxin convertible by enzymes into iota toxin proper.


Article metrics loading...

Loading full text...

Full text loading...



  1. Batty I., Glenny A.T. 1947; Titration of Cl. welchii epsilon toxins and antitoxins. Brit. J. exp. Path. 27:110
    [Google Scholar]
  2. Bosworth T.J. 1943; On a new type of toxin produced by Cl. welchii. J. comp. Path. 53:3245
    [Google Scholar]
  3. Turner A.W., Rodwell A.W. 1943; The Epsilon toxin of Cl. welchii type D. 1. Proteolytic conversion of ɛ prototoxin into ɛ toxin by trypsin and other proteases. Aust. J. exp. Biol. med. sci. 27:17
    [Google Scholar]
  4. Wilsdon A.J. 1931; Observations on the classification of B. welchii. Rep. Dir. Inst. Anim. Path. Camb. 2:53
    [Google Scholar]

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error