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Summary: Western blot analysis was used to identify antigenic components of Gardnerella vaginalis.Polypeptides bound to nitrocellulose membranes were probed with murine antisera raised to two strains of G. vaginalis. and antibody-antigen complexes were detected with 125I-labelled antimouse immunoglobulin followed by autoradiography. Although there was inter-strain variation in immunogenic polypeptide profiles, all 23 strains of G. vaginalis examined contained a common antigen of molecular mass 41 kDa. This antigen was not found in any of six other bacterial genera.
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