1887

Abstract

A 34 MDal plasmid harboured by B69 carried a gene coding for the mercuric reductase enzyme, thus promoting mercury resistance in the host strain. Mercury-sensitive variants were isolated when a hypersensitive, cured derivative of strain B69 was exposed to 10 g mercury (II) ml. The alteration in mercury transport appeared to be the result of a mutation, since a transconjugant of the mutant, which carried the mercury-resistance plasmid, showed a reduced rate of mercury volatilization compared to the parental resistant strain. In addition, more mercury was tightly bound to the mutant cells. This phenomenon represents a new aspect of bacterial resistance to mercurials.

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1983-09-01
2021-05-13
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