1887

Abstract

Summary: When the growth of strain 15TP was inhibited by iodoamphenicol, three ‘iodoamphenicol particles’ accumulated with sedimentation coefficients of 25S, 33S and 45S. The 25S and 33S particles differ in sedimentation properties from equivalent ribosome precursor particles detected during pulse-labelling of exponentially growing cells. Inhibition of a mutant, strain 15-28 (defective in ribosome assembly), by iodoamphenicol resulted in the accumulation of 38S iodoamphenicol particles that are different from the particles made by the parent. The results support the contention that assembly of 50S ribosomal subunits by the mutant is altered at an early stage.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-128-5-997
1982-05-01
2019-10-23
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-128-5-997
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error