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In yeast, fuchsin resistance at the mitochondrial level is mainly controlled by a nuclear gene (fub). Among the sensitive revertants obtained from a resistant strain of Saccharomyces cerevisiae, different suppression situations have been analysed. A cytoplasmic control of fuchsin resistance was found in one revertant. In two others, two nuclear suppressors have been identified; one of them was linked to the fub gene and exhibited a peculiar cis-trans effect.
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