1887

Abstract

Introduction:

is a rare but recognized cause of post-operative wound infection. There are very few cases reported in the literature of infection following neurosurgery.

Case presentation:

A 30-year-old woman with a history of chronic low back pain and symptoms consistent with sciatica underwent a microdiscectomy and anterior lumbar inter-body fusion for cord compression. Following surgery she developed an abscess overlying the lumbar surgical wound. Initial microbiological samples were negative on routine culture and the abscess recurred following surgical washout. Culture of a second specimen taken 1 month following the initial surgery revealed small colourless colonies that were not able to be seen on Gram stain. Molecular testing with 16S rRNA gene analysis confirmed infection and the patient was treated with long-term oral moxifloxacin.

Conclusion:

Infection with should be considered in culture-negative cases of post-operative wound infection where routine antibiotics fail. Diagnosis of can be delayed due to the fastidious nature of the organism and may require molecular techniques. Initiation of appropriate antimicrobial treatment is often associated with a good clinical outcome.

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2016-04-19
2022-01-26
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References

  1. Capoccia R., Greub G., Baud D. 2013; Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes. Curr Opin Infect Dis 26:231–240 [View Article][PubMed]
    [Google Scholar]
  2. Díaz L., Cabrera L. E., Fernández T., Ibáñez I., Torres Y., Obregón Y., Rivero Y. 2013; Frequency and antimicrobial sensitivity of Ureaplasma urealyticum Mycoplasma hominisin patients with vaginal discharge. MEDICC Rev 15:45–47[PubMed]
    [Google Scholar]
  3. Krijnen M. R., Hekker T., Algra J., Wuisman P.I.J.M., Van Royen B. J. 2006; Mycoplasma hominis deep wound infection after neuromuscular scoliosis surgery: the use of real-time polymerase chain reaction (PCR). Eur Spine J 15:Suppl 5599–603 [View Article][PubMed]
    [Google Scholar]
  4. Madoff S., Hooper D. C. 1988; Nongenitourinary infections caused by Mycoplasma hominis in adults. Rev Infect Dis 10:602–613 [View Article][PubMed]
    [Google Scholar]
  5. McCarthy K. L., Looke D. F. 2008; Successful treatment of post-neurosurgical intracranial Mycoplasma hominis infection using gatifloxacin. J Infect 57:344–346 [View Article][PubMed]
    [Google Scholar]
  6. McKechnie M. L., Hillman R. J., Jones R., Lowe P. C., Couldwell D. L., Davies S. C., King F., Kong F., Gilbert G. L. 2011; The prevalence of urogenital micro-organisms detected by a multiplex PCR-reverse line blot assay in women attending three sexual health clinics in Sydney, Australia. J Med Microbiol 60:1010–1016 [View Article][PubMed]
    [Google Scholar]
  7. Meyer R. D., Clough W. 1993; Extragenital Mycoplasma hominis infections in adults: emphasis on immunosuppression. Clin Infect Dis 17:Suppl 1S243–S249 [View Article][PubMed]
    [Google Scholar]
  8. Pailhoriès H., Rabier V., Eveillard M., Mahaza C., Joly-Guillou M.-L., Chennebault J.-M., Kempf M., Lemarié C. 2014; A case report of Mycoplasma hominis brain abscess identified by MALDI-TOF mass spectrometry. Int J Infect Dis 29:166–168 [View Article][PubMed]
    [Google Scholar]
  9. Pereyre S., Gonzalez P., De Barbeyrac B., Darnige A., Renaudin H., Charron A., Raherison S., Bébéar C., Bébéar C. M. 2002; Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis . Antimicrob Agents Chemother 46:3142–3150 [View Article][PubMed]
    [Google Scholar]
  10. Samra Z., Rosenberg S., Soffer Y. 2002; In vitro susceptibility of Mycoplasma hominis clinical isolates to tetracyclines, quinolones and macrolides. Diagn Microbiol Infect Dis 44:359–361 [View Article][PubMed]
    [Google Scholar]
  11. Song T., Ye A., Xie X., Huang J., Ruan Z., Kong Y., Song J., Wang Y., Chen J., Zhang J. 2014; Epidemiological investigation and antimicrobial susceptibility analysis of ureaplasma species and Mycoplasma hominis in outpatients with genital manifestations. J Clin Pathol 67:817–820 [View Article][PubMed]
    [Google Scholar]
  12. Taylor-Robinson D. 1996; Infections due to species of Mycoplasma Ureaplasma: an update. Clin Infect Dis 23:671–684 [View Article][PubMed]
    [Google Scholar]
  13. Taylor-Robinson D., Bébéar C. 1997; Antibiotic susceptibilities of mycoplasmas and treatment of mycoplasmal infections. J Antimicrob Chemother 40:622–630 [View Article][PubMed]
    [Google Scholar]
  14. Taylor-Robinson D., Lamont R. F. 2011; Mycoplasmas in pregnancy. BJOG 118:164–174 [View Article][PubMed]
    [Google Scholar]
  15. Waites K. B., Crabb D. M., Duffy L. B. 2008; Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother 52:3776–3778 [View Article][PubMed]
    [Google Scholar]
  16. Whitson W. J., Ball P. A., Lollis S. S., Balkman J. D., Bauer D. F. 2014; Postoperative Mycoplasma hominis infections after neurosurgical intervention. J Neurosurg Pediatr 14:212–218 [View Article][PubMed]
    [Google Scholar]
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