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JMM Case Reports JMM Case Reports

Volume 1, Issue 3

Isolation and identification of from rhinofacial mucormycosis in a diabetic patient Open Access

Abstract

Introduction:

Mucormycosis is usually an invasive mycotic disease caused by fungi in the class Mucormycetes. It often occurs in immunocompromised patients but sporadic cases without apparent immune impairment have been described.

Case presentation:

Here we report a case of rhinofacial mucormycosis due to in a 55‐year‐old diabetic female. She presented with diabetic ketoacidosis and nasal obstruction, nasal discharge and right‐sided cheek swelling following sinus surgery, which had been performed at a private hospital 1 month previously. Endoscopic biopsy was performed and the sample was sent for histopathological examination and KOH wet mount, which showed broad, pauci‐septate hyphae with right‐angle branching. The tissue was inoculated onto Sabouraud dextrose agar and white mycelial growth was obtained which turned grey with age. Morphological identification confirmed it as . antifungal susceptibility testing was performed by means of the microbroth dilution method according to CLSI Approved Standard M38‐A. The isolate was found to be susceptible to amphotericin B, itraconazole and posaconazole but resistant to voriconazole and echinocandins. Functional endoscopic sinus surgery was performed and local necrotic tissue was debrided. The patient was put on liposomal amphotericin B, with a successful outcome.

Conclusion:

Early diagnosis is critical in prevention of morbidity and mortality associated with disease.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): amphotericin B , diabetes mellitus , mucormycosis , rhinofacial mucormycosis and Rhizomucor pusillus
© 2014 The Authors
  • This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/).
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2014-09-01
2025-04-30
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Isolation and identification of Rhizomucor pusillus from rhinofacial mucormycosis in a diabetic patient
JMM Case Rep 1, e002931 (2014); https://doi.org/10.1099/jmmcr.0.002931
/content/journal/jmmcr/10.1099/jmmcr.0.002931
/content/journal/jmmcr/10.1099/jmmcr.0.002931
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