1887

JMM Case Reports

Volume 2, Issue 2

brain abscess in an immunocompromised woman Open Access

Abstract

Introduction:

is a rare cause of infection worldwide, with very few published cases. Here we report the first case to our knowledge of brain abscess caused by .

Case presentation:

Our patient, currently undergoing treatment with rituximab for non‐Hodgkin lymphoma, presented with a 2 week history of worsening headache and nuchal rigidity. Magnetic resonance imaging of the brain revealed a ring‐enhancing mass in the right temporal lobe. The abscess was surgically resected and the causative organism was identified as by culture and then 16S PCR of the rRNA gene. Our patient was successfully treated with a combination of imipenem and trimethoprim–sulfamethoxazole (15 mg kg day) for 3 months, followed by 9 months of monotherapy with trimethoprim–sulfamethoxazole.

Conclusion:

Treatment of nocardiosis remains challenging, with each species having a unique antimicrobial susceptibility profile. Our patient was successfully treated with a combination of imipenem and trimethoprim–sulfamethoxazole, followed by monotherapy with trimethoprim–sulfamethoxazole.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): brain abscess , imipenem , immunocompromised , Nocardia puris , nocardiosis and trimethroprim–sulfamethoxazole.
© 2015 The Authors
  • This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/).
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2015-04-01
2024-09-17
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Nocardia puris brain abscess in an immunocompromised woman
JMM Case Rep 2, e000020 (2015); https://doi.org/10.1099/jmmcr.0.000020
/content/journal/jmmcr/10.1099/jmmcr.0.000020
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