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The frequency of antibiotic resistance in coliform bacilli causing asymptomatic bacteriuria of pregnancy in two hospitals in West London was studied. Approximately one-fifth of the strains were resistant to at least one antibiotic. No increase in resistance was shown when these figures were compared with a previous study of symptomatic bacteriuria made in 1968–69, although both studies show an increase compared with figures obtained in 1962–63. In one-third of strains, resistance was shown to be mediated by R factors.
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