1887

Abstract

Summary

strains with enterotoxic activity can be isolated from the faeces of newborn farm animals with diarrhoea and are called enterotoxigenic (ETBF). These strains can now be detected in an in-vitro cytotoxicity assay with HT-29 cells. In this study, 146 strains (95 faecal and 40 extra-intestinal isolates) and 64 isolates belonging to species other than were tested for their ability to produce enterotoxin. Sixteen strains of ETBF were identified; all belonged to the species and represented 11% of all examined. The prevalence was similar among extraintestinal and faecal strains, 11.5% and 10%, respectively. The production of enterotoxin in clinical isolates appeared to be associated with infections where tissue destruction was more prominent. Enterotoxigenicity was not associated with the presence of a plasmid and the plasmid profiles of ETBF strains that harboured plasmids were different. These results show that enterotoxin production by human isolates of is not uncommon and could represent a new virulence factor of .

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/content/journal/jmm/10.1099/00222615-41-3-191
1994-09-01
2020-01-18
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-41-3-191
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