1887

Abstract

The genus comprises small non-enveloped viruses with a circular single-stranded DNA genome. By using PCR with degenerate primers, a novel circovirus (starling circovirus, StCV) was detected in spleen samples of wild starlings ( and ) found dead during an epidemic outbreak of septicaemic salmonellosis in northeastern Spain. Using a specific PCR, StCV was also detected in apparently healthy birds from the same population. The genome was amplified using multiply primed rolling-circle amplification and cloned. Open reading frames (ORFs) with similarities to the replication-associated protein and the capsid protein of circoviruses as well as an additional ORF encoding a protein of 106 aa were evident from the sequence. Phylogenetic analysis of circovirus genomes revealed the highest degree of similarity (67·1 %) between StCV and canary circovirus. A similar analysis of the evolutionarily conserved cytochrome gene of the circovirus host species revealed a strict co-evolution of circoviruses with their hosts; however, the circoviruses showed about a threefold higher genetic divergence than their hosts.

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2006-05-01
2019-12-15
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References

  1. Allan, G. M. & Ellis, J. A. ( 2000; ). Porcine circoviruses: a review. J Vet Diagn Invest 12, 3–14.[CrossRef]
    [Google Scholar]
  2. Altschul, S. F., Madden, T. L., Schäffer, A. A., Zhang, J., Zhang, Z., Miller, W. & Lipman, D. J. ( 1997; ). Gapped blast and psi-blast: a new generation of protein database search programs. Nucleic Acids Res 25, 3389–3402.[CrossRef]
    [Google Scholar]
  3. Arnal, M. C., Revilla, M., Marco, M. & 7 other authors ( 2005; ). Brote de salmonelosis septicémica en estorninos pintos Sturnus vulgaris. In Abstracts of the 17th Meeting of the Spanish Veterinary Pathology Society, p. 106. Jarandilla de la Vera, Cáceres, Spain. 14–16 July 2005.
  4. Bassami, M. R., Berryman, D., Wilcox, G. E. & Raidal, S. R. ( 1998; ). Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus. Virology 249, 453–459.[CrossRef]
    [Google Scholar]
  5. Chae, C. ( 2005; ). A review of porcine circovirus 2-associated syndromes and diseases. Vet J 169, 326–336.[CrossRef]
    [Google Scholar]
  6. Dean, F. B., Nelson, J. R., Giesler, T. L. & Lasken, R. S. ( 2001; ). Rapid amplification of plasmid and phage DNA using Phi29 DNA polymerase and multiply-primed rolling circle amplification. Genome Res 11, 1095–1099.[CrossRef]
    [Google Scholar]
  7. de Kloet, E. & de Kloet, S. R. ( 2004; ). Analysis of the beak and feather disease viral genome indicates the existence of several genotypes which have a complex psittacine host specificity. Arch Virol 149, 2393–2412.[CrossRef]
    [Google Scholar]
  8. Dekonenko, A., Yakimenko, V., Ivanov, A., Morozov, V., Nikitin, P., Khasanova, S., Dzagurova, T., Tkachenko, E. & Schmaljohn, C. ( 2003; ). Genetic similarity of Puumala viruses found in Finland and western Siberia and of the mitochondrial DNA of their rodent hosts suggests a common evolutionary origin. Infect Genet Evol 3, 245–257.[CrossRef]
    [Google Scholar]
  9. Esteban, J. A., Salas, M. & Blanco, L. ( 1993; ). Fidelity of Phi29 DNA polymerase. Comparison between protein-primed initiation and DNA polymerization. J Biol Chem 268, 2719–2726.
    [Google Scholar]
  10. Griffiths, C. S., Barrowclough, G. F., Groth, J. G. & Mertz, L. ( 2004; ). Phylogeny of the Falconidae (Aves): a comparison of the efficacy of morphological, mitochondrial, and nuclear data. Mol Phylogenet Evol 32, 101–109.[CrossRef]
    [Google Scholar]
  11. Hattermann, K., Schmitt, C., Soike, D. & Mankertz, A. ( 2003; ). Cloning and sequencing of duck circovirus (DuCV). Arch Virol 148, 2471–2480.[CrossRef]
    [Google Scholar]
  12. Heath, L., Martin, D. P., Warburton, L., Perrin, M., Horsfield, W., Kingsley, C., Rybicki, E. P. & Williamson, A. L. ( 2004; ). Evidence of unique genotypes of beak and feather disease virus in southern Africa. J Virol 78, 9277–9284.[CrossRef]
    [Google Scholar]
  13. Hughes, A. L. & Friedman, R. ( 2000; ). Evolutionary diversification of protein-coding genes of hantaviruses. Mol Biol Evol 17, 1558–1568.[CrossRef]
    [Google Scholar]
  14. Johne, R., Raue, R., Grund, C., Kaleta, E. F. & Müller, H. ( 2004; ). Recombinant expression of a truncated capsid protein of beak and feather disease virus and its application in serologic tests. Avian Pathol 33, 328–336.
    [Google Scholar]
  15. Kocher, T. D., Thomas, W. K., Meyer, A., Edwards, S. V., Paabo, S., Villablanca, F. X. & Wilson, A. C. ( 1989; ). Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers. Proc Natl Acad Sci U S A 86, 6196–6200.[CrossRef]
    [Google Scholar]
  16. Mankertz, A., Hattermann, K., Ehlers, B. & Soike, D. ( 2000; ). Cloning and sequencing of columbid circovirus (CoCV), a new circovirus from pigeons. Arch Virol 145, 2469–2479.[CrossRef]
    [Google Scholar]
  17. Niagro, F. D., Forsthoefel, A. N., Lawther, R. P., Kamalanathan, L., Ritchie, B. W., Latimer, K. S. & Lukert, P. D. ( 1998; ). Beak and feather disease virus and porcine circovirus genomes: intermediates between the geminiviruses and plant circoviruses. Arch Virol 143, 1723–1744.[CrossRef]
    [Google Scholar]
  18. Niel, C., Diniz-Mendes, L. & Devalle, S. ( 2005; ). Rolling-circle amplification of Torque teno virus (TTV) complete genomes from human and swine sera and identification of a novel swine TTV genogroup. J Gen Virol 86, 1343–1347.[CrossRef]
    [Google Scholar]
  19. Paez, J. G., Lin, M., Beroukhim, R. & 10 other authors ( 2004; ). Genome coverage and sequence fidelity of ϕ29 polymerase-based multiple strand displacement whole genome amplification. Nucleic Acids Res 32, e71.[CrossRef]
    [Google Scholar]
  20. Phenix, K. V., Weston, J. H., Ypelaar, I., Lavazza, A., Smyth, J. A., Todd, D., Wilcox, G. E. & Raidal, S. R. ( 2001; ). Nucleotide sequence analysis of a novel circovirus of canaries and its relationship to other members of the genus Circovirus of the family Circoviridae. J Gen Virol 82, 2805–2809.
    [Google Scholar]
  21. Raue, R., Johne, R., Crosta, L., Bürkle, M., Gerlach, H. & Müller, H. ( 2004; ). Nucleotide sequence analysis of a C1 gene fragment of psittacine beak and feather disease virus amplified by real-time PCR indicates a possible existence of pathotypes. Avian Pathol 33, 41–50.[CrossRef]
    [Google Scholar]
  22. Raue, R., Schmidt, V., Freick, M., Reinhardt, B., Johne, R., Kamphausen, L., Kaleta, E. F., Müller, H. & Krautwald-Junghanns, M.-E. ( 2005; ). A disease complex associated with pigeon circovirus infection, young pigeon disease syndrome. Avian Pathol 34, 418–425.[CrossRef]
    [Google Scholar]
  23. Rector, A., Bossart, G. D., Ghim, S. J., Sundberg, J. P., Jenson, A. B. & Van Ranst, M. ( 2004a; ). Characterization of a novel close-to-root papillomavirus from a Florida manatee by using multiply primed rolling-circle amplification: trichechus manatus latirostris papillomavirus type 1. J Virol 78, 12698–12702.[CrossRef]
    [Google Scholar]
  24. Rector, A., Tachezy, R. & Van Ranst, M. ( 2004b; ). A sequence-independent strategy for detection and cloning of circular DNA virus genomes by using multiply primed rolling-circle amplification. J Virol 78, 4993–4998.[CrossRef]
    [Google Scholar]
  25. Rector, A., Tachezy, R., Van Doorslaer, K., MacNamara, T., Burk, R. D., Sundberg, J. P. & Van Ranst, M. ( 2005; ). Isolation and cloning of a papillomavirus from a North American porcupine by using multiply primed rolling-circle amplification: the Erethizon dorsatum papillomavirus type 1. Virology 331, 449–456.[CrossRef]
    [Google Scholar]
  26. Soike, D., Albrecht, K., Hattermann, K., Schmitt, C. & Mankertz, A. ( 2004; ). Novel circovirus in mulard ducks with developmental and feathering disorders. Vet Rec 154, 792–793.[CrossRef]
    [Google Scholar]
  27. Thompson, J. D., Higgins, D. G. & Gibson, T. J. ( 1994; ). clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22, 4673–4680.[CrossRef]
    [Google Scholar]
  28. Todd, D. ( 2004; ). Avian circovirus diseases: lessons for the study of PMWS. Vet Microbiol 98, 169–174.[CrossRef]
    [Google Scholar]
  29. Todd, D., Weston, J., Ball, N. W., Borghmanns, B. J., Smyth, J. A., Gelmini, L. & Lavazza, A. ( 2001a; ). Nucleotide sequence-based identification of a novel circovirus of canaries. Avian Pathol 30, 321–325.[CrossRef]
    [Google Scholar]
  30. Todd, D., Weston, J. H., Soike, D. & Smyth, J. A. ( 2001b; ). Genome sequence determinations and analyses of novel circoviruses from goose and pigeon. Virology 286, 354–362.[CrossRef]
    [Google Scholar]
  31. Todd, D., Bendinelli, M., Biagini, P. & 8 other authors ( 2005; ). Circoviridae. In Virus Taxonomy, VIIIth Report of the International Committee for the Taxonomy of Viruses, pp. 327–334. Edited by C. M. Fauquet, M. A. Mayo, J. Maniloff, U. Desselberger & L. A. Ball. London: Elsevier/Academic Press.
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