1887

Abstract

Although G2P[4] rotaviruses are common causes of infantile diarrhoea, to date only the full genomes of the prototype (strain DS-1) and another old strain, TB-Chen, have been analysed. We report here the full genomic analyses of two Bangladeshi G2P[4] strains, MMC6 and MMC88, detected in 2005. Both the strains exhibited a DS-1-like genotype constellation. Excluding the VP4 and VP7 genes, and except for VP3 of MMC88, the MMC strains were genetically more closely related to the contemporary G2P[4] and several non-G2P[4] human strains than the prototype G2P[4] strain. However, by phylogenetic analyses, the VP2, VP3 (except MMC88), NSP1 and NSP3–5 genes of these strains appeared to share a common origin with those of the prototype strain, whilst their VP1, VP6 and NSP2 genes clustered near a caprine strain. The VP3 gene of MMC88 exhibited maximum relatedness to a local caprine strain, representing the first reported human G2P[4] strain with a gene of animal origin.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.029868-0
2011-05-01
2019-12-05
Loading full text...

Full text loading...

/deliver/fulltext/jgv/92/5/1222.html?itemId=/content/journal/jgv/10.1099/vir.0.029868-0&mimeType=html&fmt=ahah

References

  1. Abe M. , Ito N. , Morikawa S. , Takasu M. , Murase T. , Kawashima T. , Kawai Y. , Kohara J. , Sugiyama M. . ( 2009; ). Molecular epidemiology of rotaviruses among healthy calves in Japan: isolation of a novel bovine rotavirus bearing new P and G genotypes. . Virus Res 144:, 250–257. [CrossRef] [PubMed]
    [Google Scholar]
  2. Abe M. , Ito N. , Masatani T. , Nakagawa K. , Yamaoka S. , Kanamaru Y. , Suzuki H. , Shibano K. , Arashi Y. , Sugiyama M. . ( 2011; ). Whole genome characterization of new bovine rotavirus G21P[29] and G24P[33] strains provides evidence for interspecies transmission. . J Gen Virol 92:, 952–960. [CrossRef] [PubMed]
    [Google Scholar]
  3. Antunes H. , Afonso A. , Iturriza M. , Martinho I. , Ribeiro C. , Rocha S. , Magalhães C. , Carvalho L. , Branca F. , Gray J. . ( 2009; ). G2P[4] the most prevalent rotavirus genotype in 2007 winter season in an European non-vaccinated population. . J Clin Virol 45:, 76–78. [CrossRef] [PubMed]
    [Google Scholar]
  4. Bányai K. , Papp H. , Dandár E. , Molnár P. , Mihály I. , Van Ranst M. , Martella V. , Matthijnssens J. . ( 2010; ). Whole genome sequencing and phylogenetic analysis of a zoonotic human G8P[14] rotavirus strain. . Infect Genet Evol 10:, 1140–1144. [CrossRef] [PubMed]
    [Google Scholar]
  5. Chen Y. , Wen Y. , Liu X. , Xiong X. , Cao Z. , Zhao Q. , Yu Y. , Yin X. , Li C. , Fan Y. . ( 2008; ). Full genomic analysis of human rotavirus strain TB-Chen isolated in China. . Virology 375:, 361–373. [CrossRef] [PubMed]
    [Google Scholar]
  6. Collins P. J. , Martella V. , Buonavoglia C. , O’Shea H. . ( 2010; ). Identification of a G2-like porcine rotavirus bearing a novel VP4 type, P[32]. . Vet Res 41:, 73. [CrossRef] [PubMed]
    [Google Scholar]
  7. Cook J. P. , McCrae M. A. . ( 2004; ). Sequence analysis of the guanylyltransferase (VP3) of group A rotaviruses. . J Gen Virol 85:, 929–932. [CrossRef] [PubMed]
    [Google Scholar]
  8. Esona M. D. , Mijatovic-Rustempasic S. , Conrardy C. , Tong S. , Kuzmin I. V. , Agwanda B. , Breiman R. F. , Banyai K. , Niezgoda M. et al. ( 2010; ). Reassortant group A rotavirus from straw-colored fruit bat (Eidolon helvum). . Emerg Infect Dis 16:, 1844–1852.[PubMed] [CrossRef]
    [Google Scholar]
  9. Esona M. D. , Banyai K. , Foytich K. , Freeman M. , Mijatovic-Rustempasic S. , Hull J. , Kerin T. , Steele A. D. , Armah G. E. , Geyer A. . ( 2011; ). Genomic characterization of human rotavirus G10 strains from the African Rotavirus Network: relationship to animal rotaviruses. . Infect Genet Evol 11:, 237–241. [CrossRef] [PubMed]
    [Google Scholar]
  10. Estes M. K. , Kapikian A. Z. . ( 2007; ). Rotaviruses and their replication. . In Fields Virology, , 5th edn., pp. 1917–1974. Edited by Fields B. N. , Knipe D. M. , Howley P. M. , Griffin D. E. , Lamb R. A. , Martin M. A. , Roizman B. , Straus S. E. . . Philadelphia, PA:: Lippincott, Williams & Wilkins;.
    [Google Scholar]
  11. Gentsch J. R. , Glass R. I. , Woods P. , Gouvea V. , Gorziglia M. , Flores J. , Das B. K. , Bhan M. K. . ( 1992; ). Identification of group A rotavirus gene 4 types by polymerase chain reaction. . J Clin Microbiol 30:, 1365–1373.[PubMed]
    [Google Scholar]
  12. Ghosh S. , Alam M. M. , Ahmed M. U. , Talukdar R. I. , Paul S. K. , Kobayashi N. . ( 2010; a). Complete genome constellation of a caprine group A rotavirus strain reveals common evolution with ruminant and human rotavirus strains. . J Gen Virol 91:, 2367–2373. [CrossRef] [PubMed]
    [Google Scholar]
  13. Ghosh S. , Kobayashi N. , Nagashima S. , Chawla-Sarkar M. , Krishnan T. , Ganesh B. , Naik T. N. . ( 2010; b). Full genomic analysis and possible origin of a porcine G12 rotavirus strain RU172. . Virus Genes 40:, 382–388. [CrossRef] [PubMed]
    [Google Scholar]
  14. Ghosh S. , Gatheru Z. , Nyangao J. , Adachi N. , Urushibara N. , Kobayashi N. . ( 2011; ). Full genomic analysis of a simian SA11-like G3P[2] rotavirus strain isolated from an asymptomatic infant: identification of novel VP1, VP6 and NSP4 genotypes. . Infect Genet Evol 11:, 57–63 [CrossRef] [PubMed]
    [Google Scholar]
  15. Greenberg H. B. , Estes M. K. . ( 2009; ). Rotaviruses: from pathogenesis to vaccination. . Gastroenterology 136:, 1939–1951. [CrossRef] [PubMed]
    [Google Scholar]
  16. Gurgel R. Q. , Cuevas L. E. , Vieira S. C. , Barros V. C. , Fontes P. B. , Salustino E. F. , Nakagomi O. , Nakagomi T. , Dove W. et al. ( 2007; ). Predominance of rotavirus P[4]G2 in a vaccinated population, Brazil. . Emerg Infect Dis 13:, 1571–1573.[PubMed] [CrossRef]
    [Google Scholar]
  17. Heiman E. M. , McDonald S. M. , Barro M. , Taraporewala Z. F. , Bar-Magen T. , Patton J. T. . ( 2008; ). Group A human rotavirus genomics: evidence that gene constellations are influenced by viral protein interactions. . J Virol 82:, 11106–11116. [CrossRef] [PubMed]
    [Google Scholar]
  18. Hoshino Y. , Saif L. J. , Kang S. Y. , Sereno M. M. , Chen W. K. , Kapikian A. Z. . ( 1995; ). Identification of group A rotavirus genes associated with virulence of a porcine rotavirus and host range restriction of a human rotavirus in the gnotobiotic piglet model. . Virology 209:, 274–280. [CrossRef] [PubMed]
    [Google Scholar]
  19. Kirkwood C. D. , Boniface K. , Bishop R. F. , Barnes G. L. . Australian Rotavirus Surveillance Group ( 2009; ). Australian Rotavirus Surveillance Program annual report, 2008/2009. . Commun Dis Intell 33:, 382–388.[PubMed]
    [Google Scholar]
  20. Martella V. , Bányai K. , Matthijnssens J. , Buonavoglia C. , Ciarlet M. . ( 2010; ). Zoonotic aspects of rotaviruses. . Vet Microbiol 140:, 246–255. [CrossRef] [PubMed]
    [Google Scholar]
  21. Martínez M. , Amarilla A. A. , Galeano M. E. , Aquino V. H. , Fariña N. , Russomando G. , Parra G. I. . ( 2010; ). Predominance of rotavirus G2P[4] and emergence of G12P[9] strains in Asunción, Paraguay, 2006–2007. . Arch Virol 155:, 525–533. [CrossRef] [PubMed]
    [Google Scholar]
  22. Matthijnssens J. , Ciarlet M. , Heiman E. , Arijs I. , Delbeke T. , McDonald S. M. , Palombo E. A. , Iturriza-Gómara M. , Maes P. et al. ( 2008; a). Full genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains. . J Virol 82:, 3204–3219. [CrossRef] [PubMed]
    [Google Scholar]
  23. Matthijnssens J. , Ciarlet M. , Rahman M. , Attoui H. , Bányai K. , Estes M. K. , Gentsch J. R. , Iturriza-Gómara M. , Kirkwood C. D. et al. ( 2008; b). Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments. . Arch Virol 153:, 1621–1629. [CrossRef] [PubMed]
    [Google Scholar]
  24. Matthijnssens J. , Joelsson D. B. , Warakomski D. J. , Zhou T. , Mathis P. K. , Van Maaren M. H. , Ranheim T. S. , Ciarlet M. . ( 2010; ). Molecular and biological characterization of the 5 human-bovine rotavirus(WC3)-based reassortant strains of the pentavalent rotavirus vaccine, RotaTeq. . Virology 403:, 111–127. [CrossRef] [PubMed]
    [Google Scholar]
  25. Matthijnssens J. , Rahman M. , Van Ranst M. . ( 2008; c). Two out of the 11 genes of an unusual human G6P[6] rotavirus isolate are of bovine origin. . J Gen Virol 89:, 2630–2635. [CrossRef] [PubMed]
    [Google Scholar]
  26. McDonald S. M. , Matthijnssens J. , McAllen J. K. , Hine E. , Overton L. , Wang S. , Lemey P. , Zeller M. , Van Ranst M. et al. ( 2009; ). Evolutionary dynamics of human rotaviruses: balancing reassortment with preferred genome constellations. . PLoS Pathog 5:, e1000634. [CrossRef] [PubMed]
    [Google Scholar]
  27. Paul S. K. , Kobayashi N. , Nagashima S. , Ishino M. , Watanabe S. , Alam M. M. , Ahmed M. U. , Hossain M. A. , Naik T. N. . ( 2008; ). Phylogenetic analysis of rotaviruses with genotypes G1, G2, G9 and G12 in Bangladesh: evidence for a close relationship between rotaviruses from children and adults. . Arch Virol 153:, 1999–2012. [CrossRef] [PubMed]
    [Google Scholar]
  28. Pun S. B. , Nakagomi T. , Sherchand J. B. , Pandey B. D. , Cuevas L. E. , Cunliffe N. A. , Hart C. A. , Nakagomi O. . ( 2007; ). Detection of G12 human rotaviruses in Nepal. . Emerg Infect Dis 13:, 482–484. [CrossRef] [PubMed]
    [Google Scholar]
  29. Rahman M. , Matthijnssens J. , Saiada F. , Hassan Z. , Heylen E. , Azim T. , Van Ranst M. . ( 2010; ). Complete genomic analysis of a Bangladeshi G1P[8] rotavirus strain detected in 2003 reveals a close evolutionary relationship with contemporary human Wa-like strains. . Infect Genet Evol 10:, 746–754. [CrossRef] [PubMed]
    [Google Scholar]
  30. Saitou N. , Nei M. . ( 1987; ). The neighbor-joining method: a new method for reconstructing phylogenetic trees. . Mol Biol Evol 4:, 406–425.[PubMed]
    [Google Scholar]
  31. Santos N. , Hoshino Y. . ( 2005; ). Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine. . Rev Med Virol 15:, 29–56. [CrossRef] [PubMed]
    [Google Scholar]
  32. Schumann T. , Hotzel H. , Otto P. , Johne R. . ( 2009; ). Evidence of interspecies transmission and reassortment among avian group A rotaviruses. . Virology 386:, 334–343. [CrossRef] [PubMed]
    [Google Scholar]
  33. Solberg O. D. , Hasing M. E. , Trueba G. , Eisenberg J. N. . ( 2009; ). Characterization of novel VP7, VP4, and VP6 genotypes of a previously untypeable group A rotavirus. . Virology 385:, 58–67. [CrossRef] [PubMed]
    [Google Scholar]
  34. Steyer A. , Bajzelj M. , Iturriza-Gómara M. , Mladenova Z. , Korsun N. , Poljsak-Prijatelj M. . ( 2010; ). Molecular analysis of human group A rotavirus G10P[14] genotype in Slovenia. . J Clin Virol 49:, 121–125. [CrossRef] [PubMed]
    [Google Scholar]
  35. Subodh S. , Bhan M. K. , Ray P. . ( 2006; ). Genetic characterization of VP3 gene of group A rotaviruses. . Virus Genes 33:, 143–145. [CrossRef] [PubMed]
    [Google Scholar]
  36. Taniguchi K. , Wakasugi F. , Pongsuwanna Y. , Urasawa T. , Ukae S. , Chiba S. , Urasawa S. . ( 1992; ). Identification of human and bovine rotavirus serotypes by polymerase chain reaction. . Epidemiol Infect 109:, 303–312. [CrossRef] [PubMed]
    [Google Scholar]
  37. Ursu K. , Kisfali P. , Rigó D. , Ivanics E. , Erdélyi K. , Dán A. , Melegh B. , Martella V. , Bányai K. . ( 2009; ). Molecular analysis of the VP7 gene of pheasant rotaviruses identifies a new genotype, designated G23. . Arch Virol 154:, 1365–1369. [CrossRef] [PubMed]
    [Google Scholar]
  38. Vesikari T. , Matson D. O. , Dennehy P. , Van Damme P. , Santosham M. , Rodriguez Z. , Dallas M. J. , Heyse J. F. , Goveia M. G. et al. ( 2006; ). Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. . N Engl J Med 354:, 23–33. [CrossRef] [PubMed]
    [Google Scholar]
  39. Wang Y. H. , Kobayashi N. , Nagashima S. , Zhou X. , Ghosh S. , Peng J. S. , Hu Q. , Zhou D. J. , Yang Z. Q. . ( 2010; ). Full genomic analysis of a porcine-bovine reassortant G4P[6] rotavirus strain R479 isolated from an infant in China. . J Med Virol 82:, 1094–1102. [CrossRef] [PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.029868-0
Loading
/content/journal/jgv/10.1099/vir.0.029868-0
Loading

Data & Media loading...

Supplements

vol. , part 5, pp. 1222 - 1227

Comparison of the deduced amino acid sequences of the VP7 genes of strains MMC6, MMC88 and the G2P[4] LB strains with those of older G2P[4] strains and the G2 component of rotavirus vaccine, RotaTeq

GenBank accession numbers for the nucleotide sequences of the 11 gene segments of rotavirus strains LB2744, LB2764 and LB2772

. Additional primers used for obtaining the full-length nucleotide sequences of different genes of RV-A strains MMC6 and MMC88

Nucleotide sequence identities exhibited by the structural genes of group A rotavirus strains MMC6 and MC88 to those of selected human and animal rotavirus strains

Nucleotide sequence identities exhibited by the non-structural genes of group A rotavirus strains MMC6 and MMC88 to those of selected human and animal rotavirus strains [Single PDF file](71 KB)



PDF

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error