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Circoviruses consist of highly prevalent and genetically diverse porcine and avian pathogens. The genomes of cycloviruses, a proposed new genus in the family Circoviridae, were recently identified in human and chimpanzee faeces. Here, six cyclovirus and four circovirus genomes from the tissues of chickens, goats, cows, and a bat were amplified and sequenced using rolling-circle amplification and inverse PCR. A goat cyclovirus was nearly identical to a cyclovirus from a cow. USA beef contained circoviruses with >99 % similarity to porcine circovirus 2b. Circoviruses in chicken were related to those of pigeons. The close genetic similarity of a subset of cycloviruses and circoviruses replicating in distinct animal species may reflect recent cross-species transmissions. Further studies will be required to determine the impact of these highly prevalent infections on the health of farm animals.
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Journal of General Virology vol. 92 , part 4, pp. 768 - 772
Supplementary Table S1. Comparison of cycloviruses and circoviruses based on amino acid identities of the replicase protein
Supplementary Table S2. Comparison of cycloviruses and circoviruses based on amino acid identities of the capsid protein [Single Excel file](30 KB)