is a family for negative-sense RNA viruses with genomes of about 10.5–14.6 kb. These viruses are maintained in and/or transmitted by fish, reptiles, and mammals. Several orthohantaviruses can infect humans, causing mild, severe, and sometimes-fatal diseases. Hantavirids produce enveloped virions containing three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family which is available at ictv.global/report/hantaviridae.

This study was supported by the:
  • Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Award HHSN272201800013C)
    • Principle Award Recipient: JensH. Kuhn
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.

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