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Abstract

is a family for negative-sense RNA viruses with genomes of about 10.5–14.6 kb. These viruses are maintained in and/or transmitted by fish, reptiles, and mammals. Several orthohantaviruses can infect humans, causing mild, severe, and sometimes-fatal diseases. Hantavirids produce enveloped virions containing three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family which is available at ictv.global/report/hantaviridae.

Funding
This study was supported by the:
  • Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Award HHSN272201800013C)
    • Principle Award Recipient: JensH. Kuhn
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
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/content/journal/jgv/10.1099/jgv.0.001975
2024-04-08
2024-05-24
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References

  1. Spiropoulou CF, B DE. Orthohantavirus, orthonairovirus, orthobunyavirus and phlebovirus. In Howley MP, Knipe DM, Whelan SPJ. eds Fields Virology, 7th. edn Pennsylvania, USA: Wolters Kluwer/Lippincott Williams & Wilkins; 2020 pp 750–783
    [Google Scholar]
  2. Mittler E, Dieterle ME, Kleinfelter LM, Slough MM, Chandran K et al. Hantavirus entry: perspectives and recent advances. Adv Virus Res 2019; 104:185–224 [View Article] [PubMed]
    [Google Scholar]
  3. Meier K, Thorkelsson SR, Quemin ERJ, Rosenthal M. Hantavirus replication cycle-an updated structural virology perspective. Viruses 2021; 13:1561 [View Article] [PubMed]
    [Google Scholar]
  4. Vial PA, Ferrés M, Vial C, Klingström J, Ahlm C et al. Hantavirus in humans: a review of clinical aspects and management. Lancet Infect Dis 2023; 23:e371–e382 [View Article] [PubMed]
    [Google Scholar]
  5. Wolf YI, Kazlauskas D, Iranzo J, Lucía-Sanz A, Kuhn JH et al. Origins and evolution of the global RNA virome. mBio 2018; 9:e02329–18 [View Article] [PubMed]
    [Google Scholar]
  6. Huiskonen JT, Hepojoki J, Laurinmäki P, Vaheri A, Lankinen H et al. Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses. J Virol 2010; 84:4889–4897 [View Article] [PubMed]
    [Google Scholar]
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