1887

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Volume 103, Issue 10

Analysis of the genome of grapevine red blotch virus and related grabloviruses indicates diversification prior to the arrival of in North America No Access

Abstract

In this study 163 complete whole-genome sequences of the emerging pathogen grapevine red blotch virus (GRBV; genus , family ) were used to reconstruct phylogenies using Bayesian analyses on time-tipped (heterochronous) data. Using different combinations of priors, Bayes factors identified heterochronous datasets (3×200 million chains) generated from strict clock and exponential tree priors as being the most robust. Substitution rates of 3.2×10 subsitutions per site per year (95% HPD 4.3–2.1×10) across the whole of the GRBV genome were estimated, suggesting ancestral GRBV diverged from ancestral wild Vitis latent virus 1 around 9 000 years ago, well before the first documented arrival of in North America. Whole-genome analysis of GRBV isolates in a single infected field-grown grapevine across 12 years identified 12 single nucleotide polymorphisms none of which were fixed substitutions: an observation not discordant with the estimate. The substitution rate estimated here is lower than those estimated for other geminiviruses and is the first for a woody-host-infecting geminivirus.

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Keyword(s): BEAST , Geminiviridae , Grablovirus , grapevine red blotch virus , TMRCA and Vitis vinifera
© 2022 The Authors
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/content/journal/jgv/10.1099/jgv.0.001789
2022-10-07
2024-05-05
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Analysis of the genome of grapevine red blotch virus and related grabloviruses indicates diversification prior to the arrival of Vitis vinifera in North America
J. Gen. Virol. 103, 001789 (2022); https://doi.org/10.1099/jgv.0.001789
/content/journal/jgv/10.1099/jgv.0.001789
/content/journal/jgv/10.1099/jgv.0.001789
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