ICTV Virus Taxonomy Profile: Retroviridae 2021: This article is part of the ICTV Virus Taxonomy Profiles collection.

John Coffin; Jonas Blomberg; Hung Fan; Robert Gifford; Theodora Hatziioannou; Dirk Lindemann; Jens Mayer; Jonathan Stoye; Michael Tristem; Welkin Johnson; ICTV Report Consortium

doi:10.1099/jgv.0.001712

Volume 102, Issue 12

Review Article

Open Access

ICTV Virus Taxonomy Profile: Retroviridae 2021

This article is part of the ICTV Virus Taxonomy Profiles collection.

John Coffin¹, Jonas Blomberg², Hung Fan³, Robert Gifford⁴, Theodora Hatziioannou⁵, Dirk Lindemann⁶, Jens Mayer⁷, Jonathan Stoye⁸, Michael Tristem⁹, Welkin Johnson¹⁰ and ICTV Report Consortium
View Affiliations Hide Affiliations

Affiliations: ¹ Tufts University, Boston, MA 2111, USA ² Uppsala University, Sweden ³ University of California, Irvine, CA 92697-3905, USA ⁴ Center for Virus Research, Glasgow G61 1QH, UK ⁵ The Rockefeller University, New York, NY10065, USA ⁶ Technische Universität Dresden, Dresden, 01307, Germany ⁷ University of Saarland, 66421 Homburg/Saar, Germany ⁸ Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK ⁹ Imperial College London, Berkshire, SL5 7PY, UK ¹⁰ Boston College, Chestnut Hill, MA 02467, USA
*Correspondence: Welkin Johnson, [email protected]
Published: 23 December 2021 https://doi.org/10.1099/jgv.0.001712

Abstract

Viruses in the family Retroviridae are found in a wide variety of vertebrate hosts. Enveloped virions are 80–100 nm in diameter with an inner core containing the viral genome and replicative enzymes. Core morphology is often characteristic for viruses within the same genus. Replication involves reverse transcription and integration into host cell DNA, resulting in a provirus. Integration into germline cells can result in a heritable provirus known as an endogenous retrovirus. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Retroviridae, which is available at ictv.global/report/retroviridae.

Received: 10/11/2021
Accepted: 11/11/2021
Published Online: 23/12/2021

Keyword(s): AIDS , HIV , ICTV Report , Retroviridae and taxonomy

Funding

This study was supported by the:

Wellcome Trust (Award WT108418AIA)
- Principle Award Recipient: ICTVConsortium

This is an open-access article distributed under the terms of the Creative Commons Attribution License.

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.001712

2021-12-23

2024-05-06

Full text loading...

/deliver/fulltext/jgv/102/12/jgv001712.html?itemId=/content/journal/jgv/10.1099/jgv.0.001712&mimeType=html&fmt=ahah

References

Goff SP. Retroviridae . In Knipe DM, Howley PM. eds Fields Virology: Lippincott, Williams & Wilkins; 2013 pp 1424–1473
[Google Scholar]
Lindemann D, Steffen I, Pöhlmann S. Cellular entry of retroviruses. Adv Exp Med Biol 2013; 790:128–149 [View Article] [PubMed]
[Google Scholar]
Overbaugh J, Miller AD, Eiden MV. Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins. Microbiol Mol Biol Rev 2001; 65:371–389 [View Article] [PubMed]
[Google Scholar]
Coffin JM, Hughes SH, Varmus HE. Retroviruses Cold Spring Harbor (NY: Cold Spring Harbor Laboratory Press; 1997
[Google Scholar]
Lesbats P, Engelman AN, Cherepanov P. Retroviral DNA Integration. Chem Rev 2016; 116:12730–12757 [View Article] [PubMed]
[Google Scholar]
Pornillos O, Ganser-Pornillos BK. Maturation of retroviruses. Curr Opin Virol 2019; 36:47–55 [View Article] [PubMed]
[Google Scholar]
Maeda N, Fan H, Yoshikai Y. Oncogenesis by retroviruses: old and new paradigms. Rev Med Virol 2008; 18:387–405 [View Article] [PubMed]
[Google Scholar]
Krupovic M, Blomberg J, Coffin JM, Dasgupta I, Fan H et al. Ortervirales: new virus order unifying five families of reverse-transcribing viruses. J Virol 2018; 92:e00515-18 [View Article] [PubMed]
[Google Scholar]

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.001712

ICTV Virus Taxonomy Profile: Retroviridae 2021

J. Gen. Virol. 102, 001712 (2021); https://doi.org/10.1099/jgv.0.001712

/content/journal/jgv/10.1099/jgv.0.001712

Data & Media loading...

Volume 102, Issue 12

Review Article

Open Access

ICTV Virus Taxonomy Profile: Retroviridae 2021

This article is part of the ICTV Virus Taxonomy Profiles collection.

Abstract

Funding

Most read this month

Most cited Most Cited RSS feed

A tale of two clades: monkeypox viruses

Updated classification of norovirus genogroups and genotypes

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

ICTV Virus Taxonomy Profile: Parvoviridae

Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses

ICTV Virus Taxonomy Profile: Picornaviridae

ICTV Virus Taxonomy Profile: Flaviviridae

ICTV Virus Taxonomy Profile: Hepeviridae 2022

ICTV Virus Taxonomy Profile: Adenoviridae 2022

Analysis of the aphthovirus 2A/2B polyprotein ‘cleavage’ mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal ‘skip’