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Abstract
Members of the family Inoviridae are non-enveloped flexible filamentous bacteriophages (600–2500×6–10 nm) with supercoiled, circular, positive-sense, single-stranded DNA genomes of 5.5–10.6 kb, encoding 7–15 proteins. They absorb to the pili of Gram-negative bacteria and replicate their DNA by a rolling-circle mechanism with progeny released from cells by extrusion without killing the host. Phage DNA can persist extra-chromosomally or integrate into the bacterial genome. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Inoviridae, which is available at ictv.global/report/inoviridae.
- Received:
- Accepted:
- Published Online:
Funding
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Biotechnology and Biological Sciences Research Council
(Award BB/R012490/1 BBS/E/F/000PR10353)
- Principle Award Recipient: EvelienM. Adriaenssens
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Wellcome Trust
(Award WT108418AIA)
- Principle Award Recipient: ICTVConsortium
© 2021