1887

Abstract

Members of the family are non-enveloped flexible filamentous bacteriophages (600–2500×6–10 nm) with supercoiled, circular, positive-sense, single-stranded DNA genomes of 5.5–10.6 kb, encoding 7–15 proteins. They absorb to the pili of Gram-negative bacteria and replicate their DNA by a rolling-circle mechanism with progeny released from cells by extrusion without killing the host. Phage DNA can persist extra-chromosomally or integrate into the bacterial genome. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/inoviridae.

Keyword(s): ICTV Report , Inoviridae and taxonomy
Funding
This study was supported by the:
  • Biotechnology and Biological Sciences Research Council (Award BB/R012490/1 BBS/E/F/000PR10353)
    • Principle Award Recipient: EvelienM. Adriaenssens
  • Wellcome Trust (Award WT108418AIA)
    • Principle Award Recipient: ICTVConsortium
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
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/content/journal/jgv/10.1099/jgv.0.001614
2021-07-06
2024-05-04
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