1887

Abstract

A small-scale study with Mosi-guard Natural spray, an insect repellent containing Citriodiol, was performed to determine if it has virucidal activity against SARS-CoV-2. A liquid test examined the activity of the insect repellent and the individual components for virucidal activity. A surface contact test looked at the activity of the insect repellent when impregnated on a latex surface as a synthetic skin for potential topical prophylactic application. Both Mosi-guard Natural spray and Citriodiol, as well as other components of the repellent, had virucidal activity in the liquid contact test. On a latex surface used to simulate treated skin, the titre of SARS-CoV-2 was less over time on the Mosi-guard Natural-treated surface but virus was still recovered.

Funding
This study was supported by the:
  • UK Ministry of Defence
    • Principle Award Recipient: SophieJ Smither
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/content/journal/jgv/10.1099/jgv.0.001585
2021-04-23
2021-05-17
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References

  1. Citrefine website Citriodiol- a natural active ingredient for insect repellants. https://www.citrefine.com/#what-is-citriodiol 25 June 2020
  2. Clarke PD. [Patents]. Antiviral composition comprising p-methane-3,8-diol. EP1748769B1, US20070178048A1, CA2559560A1 and WO2005087209A1.
  3. Smither SJ, Eastaugh LS, Findlay JS, Lever MS. Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity. Emerg Microbes Infect 2020; 9:1415–1417 [CrossRef]
    [Google Scholar]
  4. MSDS Mosi-guard natural safety data sheet. http://ww.mosi-guard.com/Media/MSDS%20Spray.pdf 25 June 2020
  5. Smither S, Phelps A, Eastaugh L, Ngugi S, O’Brien L et al. Effectiveness of four disinfectants against Ebola virus on different materials. Viruses 2016; 8:185 [CrossRef]
    [Google Scholar]
  6. Chin AWH, Chu JTS, Perera MRA, Hui KPY, Yen H-L et al. Stability of SARS-CoV-2 in different environmental conditions. Lancet Microbe 2020; 1:e10 [CrossRef][PubMed]
    [Google Scholar]
  7. Kratzel A, Todt D, V'kovski P, Steiner S, Gultom M et al. Inactivation of severe acute respiratory syndrome coronavirus 2 by WHO-Recommended hand rub formulations and alcohols. Emerg Infect Dis 2020; 26:1592–1595 [CrossRef][PubMed]
    [Google Scholar]
  8. Suchomel M, Eggers M, Maier S, Kramer A, Dancer SJ et al. Evaluation of World health Organization–Recommended hand hygiene formulations. Emerg Infect Dis 2020; 26:2068 [CrossRef]
    [Google Scholar]
  9. Vimalanathan S, Hudson J. Anti-influenza virus activity of essential oils and vapors. Am J Essent Oil Nat Prod 2014; 2:47–53
    [Google Scholar]
  10. Choi HJ. Chemical constituents of essential oils possessing anti-influenza A/WS/33 virus activity. Osong Public Health Res Perspect 2018; 9:348–353 [CrossRef][PubMed]
    [Google Scholar]
  11. Bachir RG, Benali M. Antibacterial activity of the essential oils from the leaves of Eucalyptus globulus against Escherichia coli and Staphylococcus aureus . Asian Pac J Trop Biomed 2012; 2:739–742 [CrossRef]
    [Google Scholar]
  12. Harbourt DE, Haddow AD, Piper AE, Bloomfield H, Kearney BJ et al. Modeling the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on skin, currency, and clothing. Pre-print
    [Google Scholar]
  13. Hirose R, Ikegaya H, Naito Y, Watanabe N, Yoshida T et al. Survival of SARS-CoV-2 and influenza virus on the human skin: importance of hand hygiene in COVID-19. Clin Infect Dis 2020; 3:ciaa1517
    [Google Scholar]
  14. Matson MJ, Yinda CK, Seifert SN, Bushmaker T, Fischer RJ et al. Effect of environmental conditions on SARS-CoV-2 stability in human nasal mucus and sputum. Emerg Infect Dis 2020; 26:2276–2278 [CrossRef]
    [Google Scholar]
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