1887

Abstract

Viruses in the family have a circular genome of 3.0 kb with three open reading frames. The packaged genome is inferred to be single-stranded DNA by analogy to related viruses. Redondoviruses were discovered through metagenomic sequencing methods in samples from human subjects and are inferred to replicate in humans. Evidence of redondovirus infection is associated with periodontitis and critical illness, but redondoviruses have not been shown to be the causative agent of any diseases. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/redondoviridae.

Funding
This study was supported by the:
  • National Science Foundation (Award DGE-1321851)
    • Principle Award Recipient: Not Applicable
  • National Institutes of Health (Award T32-AI-007324)
    • Principle Award Recipient: Frederic D. Bushman
  • National Institutes of Health (Award R01-HL113252)
    • Principle Award Recipient: Ronald G. Collman
  • National Institutes of Health (Award R01-HL113252)
    • Principle Award Recipient: Frederic D. Bushman
  • National Institutes of Health (Award R61-HL137063)
    • Principle Award Recipient: Ronald G. Collman
  • Wellcome Trust (Award WT108418AIA)
    • Principle Award Recipient: ICTV Consortium
Loading

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.001526
2020-12-01
2021-07-29
Loading full text...

Full text loading...

/deliver/fulltext/jgv/102/1/vir001526.html?itemId=/content/journal/jgv/10.1099/jgv.0.001526&mimeType=html&fmt=ahah

References

  1. Abbas AA, Taylor LJ, Dothard MI, Leiby JS, Fitzgerald AS et al. Redondoviridae, a family of small, circular DNA viruses of the human oro-respiratory tract associated with periodontitis and critical illness. Cell Host Microbe 2019; 25:719–729 [View Article][PubMed]
    [Google Scholar]
  2. Mankertz A, Persson F, Mankertz J, Blaess G, Buhk HJ. Mapping and characterization of the origin of DNA replication of porcine circovirus. J Virol 1997; 71:2562–2566 [View Article][PubMed]
    [Google Scholar]
  3. Cui L, Wu B, Zhu X, Guo X, Ge Y et al. Identification and genetic characterization of a novel circular single-stranded DNA virus in a human upper respiratory tract sample. Arch Virol 2017; 162:3305–3312 [View Article][PubMed]
    [Google Scholar]
  4. Abbas AA, Diamond JM, Chehoud C, Chang B, Kotzin JJ et al. The perioperative lung transplant virome: torque teno viruses are elevated in donor lungs and show divergent dynamics in primary graft dysfunction. Am J Transplant 2017; 17:1313–1324 [View Article][PubMed]
    [Google Scholar]
  5. Abbas AA, Young JC, Clarke EL, Diamond JM, Imai I et al. Bidirectional transfer of Anelloviridae lineages between graft and host during lung transplantation. Am J Transplant 2019; 19:1086–1097 [View Article][PubMed]
    [Google Scholar]
  6. Clarke EL, Lauder AP, Hofstaedter CE, Hwang Y, Fitzgerald AS et al. Microbial lineages in sarcoidosis. A metagenomic analysis tailored for low-microbial content samples. Am J Respir Crit Care Med 2018; 197:225–234 [View Article][PubMed]
    [Google Scholar]
  7. Shi B, Chang M, Martin J, Mitreva M, Lux R et al. Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis. mBio 2015; 6:e01926–14 [View Article][PubMed]
    [Google Scholar]
  8. Califf KJ, Schwarzberg-Lipson K, Garg N, Gibbons SM, Caporaso JG et al. Multi-Omics analysis of periodontal pocket microbial communities pre- and posttreatment. mSystems 2017; 2:e:00016-17 [View Article][PubMed]
    [Google Scholar]
  9. Lázaro-Perona F, Dahdouh E, Román-Soto S, Jiménez-Rodríguez S, Rodríguez-Antolín C et al. Metagenomic detection of two vientoviruses in a human sputum sample. Viruses 2020; 12:327 [View Article]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.001526
Loading
/content/journal/jgv/10.1099/jgv.0.001526
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error