The family includes viruses with flexuous filamentous virions that are 470–800 nm in length and 12–13 nm in diameter. Alphaflexiviruses have a single-stranded, positive-sense RNA genome of 5.5–9 kb. They infect plants and plant-infecting fungi. They share a distinct lineage of alphavirus-like replication proteins that is unusual in lacking any recognized protease domain. With a single exception, cell-to-cell and long-distance movement is facilitated by triple gene block proteins in plant-infecting genera. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family which is available at www.ictv.global/report/alphaflexiviridae.

Keyword(s): Alphaflexiviridae , ICTV and taxonomy
This study was supported by the:
  • Wellcome Trust (Award WT108418AIA)
    • Principle Award Recipient: ICTV Consortium
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.

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  1. Martelli GP, Adams MJ, Kreuze JF, Dolja VV. Family Flexiviridae: a case study in virion and genome plasticity. Annu Rev Phytopathol 2007; 45:73–100 [View Article][PubMed]
    [Google Scholar]
  2. Vaira AM, Kreuze J, Hammond J, Pearson MN, Martelli GP et al. Alphaflexiviridae . In King AMQ, Lefkowitz EJ, Adams MJ, Carstens EB. (editors) Virus Taxonomy, Ninth Report of the International Committee on Taxonomy of Viruses Oxford: Elsevier; 2011 pp 904–919
    [Google Scholar]
  3. Batten JS, Yoshinari S, Hemenway C. Potato virus X: a model system for virus replication, movement and gene expression. Mol Plant Pathol 2003; 4:125–131 [View Article][PubMed]
    [Google Scholar]
  4. van den Born E, Omelchenko MV, Bekkelund A, Leihne V, Koonin EV et al. Viral AlkB proteins repair RNA damage by oxidative demethylation. Nucleic Acids Res 2008; 36:5451–5461 [View Article][PubMed]
    [Google Scholar]
  5. Verchot-Lubicz J, Torrance L, Solovyev AG, Morozov SY, Jackson AO et al. Varied movement strategies employed by triple gene block-encoding viruses. Mol Plant Microbe Interact 2010; 23:1231–1247 [View Article][PubMed]
    [Google Scholar]

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