1887

Abstract

Summary

The coliphages T1, T3 and T7 rapidly lost infectivity when incubated at 60° in saline-citrate medium. From the survivors of heat-inactivated wild-type phage stocks heat-stable () mutants were isolated, which all had a reduced buoyant density. The mutant phages of T3 and T7 contained 3 to 5% less DNA than their wild-type parent, while no loss of DNA could be detected for T1 mutants. This correlation between heat stability and reduced density was confirmed by showing that a mutant of T3 selected for its lighter density had also mutated to heat-stability.

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/content/journal/jgv/10.1099/0022-1317-9-1-35
1970-10-01
2019-11-20
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-9-1-35
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