1887

Abstract

The low-affinity nerve-growth factor receptor p75 interacts with the rabies virus (RV) glycoprotein and serves as a receptor for RV. The genus comprises seven genotypes (GTs) of rabies and rabies-related viruses. The ability of p75 to interact with the glycoprotein of representative lyssaviruses from each GT was investigated. This investigation was based on a specific binding assay between BSR cells infected with a lyssavirus and (Sf21) cells expressing p75 on the cell surface. A specific interaction was observed with the glycoprotein of GT 1 RV (challenge virus standard or Pasteur virus strains) as well as wild-type RV and the glycoprotein of GT 6 European bat lyssavirus type 2. In contrast, no interaction was detected with the glycoprotein of lyssaviruses of GTs 2–5 and 7. Therefore, p75 is only a receptor for some lyssavirus glycoproteins, indicating that the other GTs must use an alternative specific receptor.

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2001-12-01
2020-11-25
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References

  1. Badrane H., Bahloul C., Perrin P., Tordo N.. 2001; Evidence of two lyssavirus phylogroups with distinct pathogenicity and immunogenicity. Journal of Virology75:3268–3276
    [Google Scholar]
  2. Bahloul C., Jacob Y., Tordo N., Perrin P.. 1998; DNA-based immunization for exploring the enlargement of immunological cross-reactivity against the lyssaviruses. Vaccine16:417–425
    [Google Scholar]
  3. Bourhy H., Kissi B., Tordo N.. 1993; Molecular diversity of the Lyssavirus genus. Virology194:70–81
    [Google Scholar]
  4. Broughan J. H., Wunner W. H.. 1995; Characterization of protein involvement in rabies binding to BHK-21 cells. Archives of Virology140:75–93
    [Google Scholar]
  5. Chao M. V.. 1994; The p75 neurotrophin receptor. Journal of Neurobiology25:1373–1385
    [Google Scholar]
  6. Colston E., Racaniello V. R.. 1994; Soluble receptor-resistant poliovirus mutants identify surface and internal capsid residues that control interaction with the cell receptor. EMBO Journal13:5855–5862
    [Google Scholar]
  7. Dechant G., Barde Y.-A.. 1997; Signalling through the neurotrophin receptor p75NTR. Current Opinion in Neurobiology7:413–418
    [Google Scholar]
  8. Fekadu M., Shaddock J. H., Sanderlin D. W., Smith J. S.. 1988; Efficacy of rabies vaccines against Duvenhage virus isolated from European house bats ( Eptesicus serotinus ), classic rabies and rabies-related virus. Vaccine6:533–539
    [Google Scholar]
  9. Gaudin Y., Ruigrok R., Tuffereau C., Knossow M., Flamand A.. 1992; Rabies glycoprotein is a trimer. Virology187:627–632
    [Google Scholar]
  10. Gould A. R., Hyatt A. D., Lunt R., Kattenbelt J. A., Hengstberger S., Blacksell S. D.. 1998; Characterisation of a novel lyssavirus isolated from Pteroid bats in Australia. Virus Research54:165–187
    [Google Scholar]
  11. Hsu E. C., Sarangi F., Iorio C., Sidhu M., Udem S., Dillehay D. L., Xu W., Rota P. A., Bellini W. J., Richardson C. D.. 1998; A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells. Journal of Virology72:2905–2916
    [Google Scholar]
  12. Jackson A. C., Park H.. 1999; Experimental rabies virus infection of p75 neurotrophin receptor-deficient mice. Acta Neuropathology98:641–644
    [Google Scholar]
  13. Jallet C., Jacob Y., Bahloul C., Drings A., Desmézières E., Tordo N., Perrin P.. 1999; Chimeric lyssavirus glycoproteins with increased immunological potential. Journal of Virology73:225–233
    [Google Scholar]
  14. King A., Crick J.. 1988; Rabies-related viruses In Rabies . pp117–199 Edited by Campbell J. B., Charlton K. M.. Boston: Kluwer;
  15. Lentz T. L., Wilson P. T., Hawrot E., Speicher D. W.. 1984; Amino acid sequence similarity between rabies virus glycoprotein and snake curaremimetic neurotoxins. Science226:847–848
    [Google Scholar]
  16. Lentz T. L., Benson R. J., Klimowicz D., Wilson P. T., Hawrot E.. 1986; Binding of rabies virus to purified Torpedo acetylcholine receptor. Brain Research1:211–219
    [Google Scholar]
  17. Matsura Y., Possee R. D., Overton H. A., Bishop D. H.. 1987; Baculovirus expression vectors: the requirement for high level expression of proteins, including glycoproteins. Journal of General Virology68:1233–1250
    [Google Scholar]
  18. Mebatsion T., Weiland F., Conzelmann K.-K.. 1999; Matrix protein of rabies virus is responsible for the assembly and budding of bullet-shaped particles and interacts with the transmembrane spike glycoprotein G. Journal of Virology73:242–250
    [Google Scholar]
  19. Murphy F., Harrison A., Washington C., Winn M., Bauer S.. 1973; Comparative pathogenesis of rabies and rabies-like viruses. Laboratory Investigation29:1–16
    [Google Scholar]
  20. Perrin P.. 1996; Techniques for the preparation of rabies conjugates In Laboratory Techniques in Rabies. pp433–445 Edited by Meslin F.-X., Kaplan M., Koprowski H.. Geneva: World Health Organization;
  21. Perrin P., Portnoi D., Sureau P.. 1982; Etude de l’adsorption et de la pénétration du virus rabique: interactions avec les cellules BHK-21 et des membranes artificielles. Annales Virologie133:403–422
    [Google Scholar]
  22. Perrin P., Thibodeau L., Sureau P.. 1985; Rabies immunosome (subunit vaccine) structure and immunogenicity. Pre- and post-exposure treatment. Vaccine3:325–332
    [Google Scholar]
  23. Perrin P., Tino de Franco M., Jallet C., Fouque F., Morgeaux S., Tordo N., Colle J.-H.. 1996; The antigen-specific cell-mediated immune response in mice is suppressed by infection with pathogenic lyssaviruses. Research in Virology147:289–299
    [Google Scholar]
  24. Rupprecht C.. 1991; Antigenic relationships of lyssavirus In The Natural History of Rabies. pp69–100 Edited by Baer G.. Boca Raton, FL: CRC Press;
  25. Rupprecht C., Dietzschold B., Koprowski H.. 1994; Lyssaviruses. Current Topics in Microbiology and Immunology187:1–339
    [Google Scholar]
  26. Saeki K., Ohtsuka N., Taguchi F.. 1997; Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants. Journal of Virology71:9024–9031
    [Google Scholar]
  27. Sato M., Maeda N., Yoshida H., Urade M., Saito S., Miyazaki T., Shibata T., Watanabe M.. 1977; Plaque formation of herpes virus hominis type 2 and rubella virus in variants isolated from the colonies of BHK-21/WI-2 cells formed in soft agar. Archives of Virology53:269–273
    [Google Scholar]
  28. Schneider L., Dietzschold B., Dierks R., Mathaeus W., Enzman P., Strohmaier K.. 1973; Rabies group-specific ribonucleoprotein antigen and test system for grouping and typing rhabdoviruses. Journal of Virology11:748–755
    [Google Scholar]
  29. Seganti L., Superti F., Bianchi S., Orsi N., Divizia M., Pana A.. 1990; Susceptibility of mammalian, avian, fish, and mosquito cell lines to rabies infection. Archives of Virology34:155–163
    [Google Scholar]
  30. Smith J., Yager P., Baer G.. 1996; A rapid fluorescent focus inhibition test (RFFIT) for determining virus-neutralizing antibody In Laboratory Techniques in Rabies . pp181–189 Edited by Meslin F.-X., Kaplan M., Koprowski H. Geneva: World Health Organization;
  31. Superti F., Seganti L., Tsiang H., Orsi N.. 1984; Role of phospholipids in rhabdovirus attachment to CER cell. Archives of Virology81:321–328
    [Google Scholar]
  32. Superti F., Hauttecoeur B., Morelec M. J., Goldoni P., Bizzini B., Tsiang H.. 1986; Involvement of gangliosides in rabies virus infection. Journal of General Virology67:47–56
    [Google Scholar]
  33. Tatsuo H., Ono N., Tanaka K., Yanagi Y.. 2000; SLAM (CDw150) is a cellular receptor for measles virus. Nature406:893–897
    [Google Scholar]
  34. Thoulouze M.-I., Lafage M., Schachner M., Hartmann U., Cremer H., Lafon M.. 1998; The neuronal cell adhesion molecule is a receptor for rabies virus. Journal of Virology72:7181–7190
    [Google Scholar]
  35. Tuffereau C., Bénéjean J., Roque-Afonso A-M., Flamand A., Fishman M. C.. 1998a; Neuronal cell surface molecules mediate specific binding to rabies virus glycoprotein expressed by a recombinant baculovirus on the surfaces of lepidopteran cells. Journal of Virology72:1085–1091
    [Google Scholar]
  36. Tuffereau C., Bénéjean J., Blondel D., Kieffer B., Flamand A.. 1998b; Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus. EMBO Journal17:7250–7259
    [Google Scholar]
  37. Wiktor T., Gyorgy E., Schlumberger D., Sokol F., Koprowski H.. 1973; Antigenic properties of rabies virus components. Journal of Immunology110:269–276
    [Google Scholar]
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