1887

Abstract

Twenty-one different mumps virus isolates from Sweden and Japan collected over 25 years were compared by nucleotide sequence analysis of the small hydrophobic (SH) protein gene, and the deduced 57 amino acid sequences of the coding part of the gene were aligned with published sequences of viral isolates from the USA, the UK, Sweden and Japan. Five genotypes were found which, in accordance with previously used nomenclature, were named A to E. Genotypes A, C, D and E were found in Europe and genotype B was found in Japan. Amino acid signature sequence motifs specific for each genotype were identified. A triplet of three amino acids at positions 28-30 was the most characteristic. Different genotypes can circulate simultaneously in a given geographical location. In Stockholm, genotypes A and D or C and D were found over different time periods. In contrast, only genotype B was found in Japan.

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1997-01-01
2022-01-21
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References

  1. Brown E. G., Furesz J., Dimmock K., Yarosh W., Contreras G. 1991; Nucleotide sequence analysis of Urabe mumps vaccine strain that caused meningitis in vaccine recipients. Vaccine 9:840–842
    [Google Scholar]
  2. Elango N. 1989; Complete nucleotide sequence of the matrix protein mRNA of mumps virus. Virology 168:426–428
    [Google Scholar]
  3. Elango N., Varsanyi T. M., Kövamees J., Norrby E. 1988; Molecular cloning and characterization of six genes, determination of gene order and intergenic sequences and leader sequence of mumps virus. Journal of General Virology 69:2893–2900
    [Google Scholar]
  4. Elango N., Kövamees J., Varsanyi T. M., Norrby E. 1989; mRNA sequences and deduced amino acid sequence of the mumps virus small hydrophobic protein gene. Journal of Virology 63:1413–1415
    [Google Scholar]
  5. Elliott G. D., Afzal M. A., Martin S. J., Rima B. K. 1989; Nucleotide sequence of the matrix, fusion and putative SH protein genes of mumps virus and their deduced amino acid sequences. Virus Research 12:61–75
    [Google Scholar]
  6. Elliott G. D., Yeo R. P., Afzal M. A., Simpson E. J. B., Curran J. A., Rima B. K. 1990; Strain-variable editing during transcription of the P gene of mumps virus may lead to the generation of non-structural proteins NS1 (V) and NS2. Journal of General Virology 71:1555–1560
    [Google Scholar]
  7. Enders J. F., Levens J. H., Stokes J.Jr Morris E. P., Berenberg W. 1946; Attenuation of virulence with retention of antigenicity of mumps virus after passage in embryonated egg. Journal of Immunology 54:283–291
    [Google Scholar]
  8. Felsenstein J. 1988; Phylogenies from molecular sequences: interference and reliability. Annual Review of Genetics 22:521–565
    [Google Scholar]
  9. Forsey T., Mawn J. A., Yates P. J., Bentley M. L., Minor P. D. 1990; Differentiation of vaccine and wild mumps viruses using the polymerase chain reaction and dideoxynucleotide sequencing. Journal of General Virology 71:987–990
    [Google Scholar]
  10. Kövamees J., Rydbeck R., Örvell C., Norrby E. 1990; Hemagglutinin-neuraminidase (HN) amino acid alterations in neutralization escape mutants of Kilham mumps virus. Virus Research 17:119–130
    [Google Scholar]
  11. Künkel U., Schreier E., Siegl G., Schultze D. 1994; Molecular characterization of mumps virus strains circulating during an epidemic in Eastern Switzerland 1992/1993. Archives of Virology 136:433–438
    [Google Scholar]
  12. Künkel U., Driesel G., Henning U., Gerike E., Willers H., Schreier E. . 1995; Differentiation of vaccine and wild mumps viruses by polymerase chain reaction and nucleotide sequencing of the SH gene. Journal of Medical Virology 45:121–126
    [Google Scholar]
  13. McCarthy M., Johnson R. T. 1980; Comparison of the structural polypeptides of five strains of mumps virus. Journal of General Virology 46:15–27
    [Google Scholar]
  14. Rima B. K., Alexander D. J., Billeter M. A., Collins P. L., Kingsbury D. W., Lipkind M. A., Nagai Y., Örvell C., Pringle C. R., ter Meulen V. 1995 The Paramyxoviridae. In Virus Taxonomy. Sixth Report of the International Committee on Taxonomy of Viruses pp 268–274 Murphy F. A., Fauquet C. M., Bishop D. H. L., Ghabrial S. A., Jarvis A. W., Martelli G. P., Mayo M. A., Summers M. D. Edited by Vienna & New York: Springer-Verlag;
    [Google Scholar]
  15. Takeuchi K., Tanabayashi K., Hishiyama M., Yamada A., Sugiura A. 1989; Cloning and sequencing of the fusion protein gene of mumps virus (Miyahara strain). Nucleic Acids Research 17:5839
    [Google Scholar]
  16. Takeuchi K., Tanabayashi K., Hishiyama M., Yamada A., Sugiura A. 1991; Variations of nucleotide sequences and transcription of the SH gene among mumps virus strains. Virology 181:364–366
    [Google Scholar]
  17. Tanabayashi K., Takeuchi K., Hishiyama M., Yamada A., Tsurudome M., Sugiura A. 1990; Nucleotide sequence of the leader and nucleocapsid protein gene of mumps virus and epitope mapping with the in vitro expressed nucleocapsid protein. Virology 177:124–130
    [Google Scholar]
  18. Waris M. 1990; Pattern of respiratory syncytial virus epidemics in Finland: two-year cycles with alternating prevalence of groups A and B. Journal of Infectious Diseases 163:464–469
    [Google Scholar]
  19. Waxham M. N., Server A. C., Goodman H. W., Wolinsky J. S. 1987; Cloning and sequencing of the mumps fusion protein gene. Virology 159:381–388
    [Google Scholar]
  20. Waxham M. N., Aronowski J., Server A. C., Wolinsky J. S., Smith J. A., Goodman H. W. 1988; Sequence determination of the mumps virus HN gene. Virology 164:318–325
    [Google Scholar]
  21. Yamada A., Takeuchi K., Tanabayashi K., Hishiyama M., Sugiura A. 1989; Sequence variation of the P gene among mumps virus strains. Virology 172:374–376
    [Google Scholar]
  22. Yamanishi K., Takahashi M., Kurimura T., Ueda S., Minekawa Y., Ogiono T., Suzuki N., Baba K., Okuno Y. 1970; Studies on live mumps vaccine. III. Evaluation of newly developed live mumps vaccine. Biken Journal 13:157–161
    [Google Scholar]
  23. Yeo R. P., Afzal M. A., Forsey T., Rima B. K. 1993; Identification of a new mumps virus lineage by nucleotide sequence analysis of the SH gene of ten different strains. Archives of Virology 128:371–377
    [Google Scholar]
  24. Yun Z. B., Lindh G., Weiland O., Johansson B., Sönnerborg A. 1993; Detection of hepatitis C virus (HCV) RNA by PCR related to HCV antibodies in serum and liver histology in Swedish blood donors. Journal of Medical Virology 39:57–61
    [Google Scholar]
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