1887

Abstract

A virus causing Jembrana disease in Bali cattle () was demonstrated to have characteristics of a retrovirus. Reverse transcriptase activity was detected in virus purified by sucrose gradient centrifugation. Electron microscopic examination of tissue from the affected cattle indicated that the virus matured by C-type budding through the plasma membrane and into intracytoplasmic vacuoles of cells in lymphoid tissue, with the formation of circular enveloped virus particles ranging in diameter from 96 to 124 nm with an eccentric nucleoid. Western immunoblotting using sera from recovered animals demonstrated virus proteins of 100K, 45K, 42K, 33K, 26K, 16K and 14K. The 26K protein of Jembrana disease virus cross-reacted in Western blots with the 26K capsid protein of bovine immunodeficiency virus (BIV). The apparent morphogenesis, protein structure and antigenic relationship with BIV suggested the virus was a lentivirus.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-74-9-1765
1993-09-01
2023-05-29
Loading full text...

Full text loading...

/deliver/fulltext/jgv/74/9/JV0740091765.html?itemId=/content/journal/jgv/10.1099/0022-1317-74-9-1765&mimeType=html&fmt=ahah

References

  1. Battles JK, Hu MY, Rasmussen L, Tobin GJ. 1992; Immunological characterization of the gag gene products of bovine immunodeficiency virus.. Journal of Virology 66:6868–6877
    [Google Scholar]
  2. Budiarso IT. 1980; The pathology of Jembrana disease.. Media Veteriner 2:60–68
    [Google Scholar]
  3. Carpenter S, Miller LD, Alexandersen S, Whetstone CA, Van Der Maaten MJ, Viuff B, Wannemuehler Y, Miller JM, Roth JA. 1992; Characterization of early pathogenic effects after experimental infection of calves with bovine immunodeficiency-like virus.. Journal of Virology 66:1074–1083
    [Google Scholar]
  4. Chan WL, Mitchison NA. 1982; The use of somatic cell hybrids for the production of monospecific viral antibodies.. Edited by Howard C. R. New Developments in Practical Virology New York: Alan R. Liss.; pp In 125–141
    [Google Scholar]
  5. Cheevers WP, McGuire TC. 1988; The lentiviruses: maedi/ visna, caprine arthritis-encephalitis, and equine infectious anemia.. Advances in Virus Research 34:189–215
    [Google Scholar]
  6. Dharma DMN, Budiantono A, Campbell RSF, Ladds PW. 1991; Studies on experimental Jembrana disease in Bali cattle. III. Pathology.. Journal of Comparative Pathology 105:397–414
    [Google Scholar]
  7. Gonda MA. 1992; Bovine immunodeficiency virus.. AIDS 6:759–776
    [Google Scholar]
  8. Gonda MA, Braun MJ, Carter SG, Kost TA, Bess JW, Arthur LO, Van Der Maaten MJ. 1987; Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus.. Nature, London 330:388–391
    [Google Scholar]
  9. Gregersen JP, Wege H, Preiss L, Jentsch KD. 1988; Detection of human immunodeficiency virus and other retroviruses in cell culture supernatants by a reverse transcriptase microassay.. Journal of Virological Methods 19:161–168
    [Google Scholar]
  10. Hartaningsih N, Wilcox GE, Kertayadnya G, Astawa M. 1993 a; Antibody response to Jembrana disease virus in Bali cattle.. Veterinary Microbiology (in press).
    [Google Scholar]
  11. Hartaningsih N, Wilcox GE, Dharma DMN, Soetrisono M. 1993 b; Distribution of Jembrana disease in cattle in Indonesia.. Veterinary Microbiology (in press).
    [Google Scholar]
  12. Malmquist WA, Van Der Maaten MJ, Boothe AD. 1969; Isolation, immunodiffusion, immunofluorescence, and electron microscopy of a syncytial virus of lymphosarcomatous and apparently normal cattle.. Cancer Research 29:188–200
    [Google Scholar]
  13. Narayan O, Clements JE. 1990; Lentiviruses.. Edited by Fields B. N., Knipe D. M. Virology, 2nd edn.. New York: Raven Press.; pp In 15711589
    [Google Scholar]
  14. Palmer E, Sporborg C, Harrison A, Martin M. L, Feorino P. 1985; Morphology and immunoelectron microscopy of AIDS virus.. Archives of Virology 85:189–196
    [Google Scholar]
  15. Ressang AA, Budiarso IT, Soeharsono S. 1985; Jembrana disease. Its similarity to bovine erhlichiosis.. Workshop on Diseases caused by leucocytic Rickettsia in Man and Animals. University of Illinois: Urbana-Champaign, Illinois.;
    [Google Scholar]
  16. Soeharsono S, Hartaningsih N, Soetrisono M, Kertayadnya G, Wilcox GE. 1990; Studies of experimental Jembrana disease in Bali cattle. I. Transmission and persistence of the infectious agent in ruminants and pigs, and resistance of recovered cattle to reinfection.. Journal of Comparative Pathology 103:49–59
    [Google Scholar]
  17. Soesanto M, Soeharsono S, Budiantono A, Sulistyana K, Tenaya M, Wilcox GE. 1990; Studies on experimental Jembrana disease in Bali cattle. II. Clinical signs and haematological changes.. Journal of Comparative Pathology 103:61–71
    [Google Scholar]
  18. Teich N. 1984; Taxonomy of retroviruses.. Edited by Weiss R., Teich N., Varmus H., Coffin J. RNA Tumor Viruses, 2nd edn.. New York: Cold Spring Harbor Laboratory.; pp In 25207
    [Google Scholar]
  19. Teuscher E, Ramachandran S, Harding HP. 1981; Observations on the pathology of ‘Jembrana disease’ in Bali cattle.. Zentralblatt fur Veterinarmedizin Reihe A 28:608–622
    [Google Scholar]
  20. Van Der Maaten MJ, Boothe AD, Seger CL. 1972; Isolation of a virus from cattle with persistent lymphocytosis.. Journal of the National Cancer Institute 49:1649–1657
    [Google Scholar]
  21. Whetstone CA, Van Der Maaten MJ, Miller JM. 1991; A Western blot assay for the detection of antibodies to bovine immunodeficiency-like virus in experimentally inoculated cattle, sheep, and goats.. Archives of Virology 116:119–131
    [Google Scholar]
  22. Wilcox GE, Kertayadnya G, Hartaningsih N, Dharma DMN, Soeharsono S, Robertson T. 1992; Evidence for a viral aetiology of Jembrana disease in Bali cattle.. Veterinary Microbiology 33:367–374
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-74-9-1765
Loading
/content/journal/jgv/10.1099/0022-1317-74-9-1765
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error