1887

Abstract

A phylogenetic tree based on the VP1 sequences of type O foot-and-mouth disease virus (FMDV) has been derived. Direct sequencing of PCR products has been used to obtain the VP1 gene sequences of new isolates. The tree exhibits four main lineages that largely correlate with the geographical origin of isolates. The analysis supports a close relationship between European O1 field isolates and vaccine strains, with the exception of O Thalheim Aus/81 and O Wuppertal Ger/82 which were probably of non-European origin. Analysis of nucleotide substitutions indicates that synonymous mutations play a major role in FMDV evolution.

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1993-10-01
2022-01-26
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References

  1. Acharya R., Fry E., Stuart D., Rowlands D., Brown F. 1989; Three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution. Nature, London 337:709–716
    [Google Scholar]
  2. Armstrong R. M., Rendle R. A. S. T., Ferris N. P., Samuel A. R., Knowles N. J. 1991; Genetic and antigenic studies on foot-and-mouth disease viruses isolated from samples collected in Turkey in 1991. Report of the Session of the Research Group of the Standing Technical Committee of the European Commission for the Control of Foot-and-Mouth Disease, Ankara, Turkey pp 63–69
    [Google Scholar]
  3. Barnett P. V., Ouldridge E. J., Rowlands D. J., Brown F., Parry N. R. 1989; Neutralizing epitopes of type O foot-and-mouth disease virus. I. Identification and characterization of three functionally independent, conformational sites. Journal of General Virology 70:1483–1491
    [Google Scholar]
  4. Baxt B., Vakharia V., Moore D. M., Franke A. J., Morgan D. O. 1989; Analysis of neutralizing antigenic sites on the surface of type A12 foot-and-mouth disease virus. Journal of Virology 63:2143–2151
    [Google Scholar]
  5. Beck E., Strohmaier K. 1987; Subtyping of European foot-and-mouth disease virus strains by nucleotide sequence determination. Journal of Virology 61:1621–1629
    [Google Scholar]
  6. Brown F. 1993; New approaches to vaccination against foot-and-mouth disease. Vaccine 10:1022–1026
    [Google Scholar]
  7. Carrillo C., Dopazo J., Moya A., Gonzalez M., Martínez M. A., Sáiz J. C., Sobrino F. 1990; Comparison of vaccine strains and the virus causing the 1986 foot-and-mouth disease outbreak in Spain: epizootiological analysis. Virus Research 15:45–56
    [Google Scholar]
  8. Cheung A., DeLamarter J., Weiss S., Küpper H. 1983; Comparison of the major antigenic determinants of foot-and-mouth disease virus. Journal of Virology 48:451–459
    [Google Scholar]
  9. Domingo E., Mateu M. G., Martínez M. A., Dopazo J., Moya A., Sobrino F. 1990; Genetic variability and antigenic diversity of foot-and-mouth disease virus. Applied Virology Research 2:233–266
    [Google Scholar]
  10. Dopazo J. 1993; Estimating errors and confidence intervals for branch lengths in phylogenetic trees by a bootstrap approach. Journal of Molecular Evolution (in press)
    [Google Scholar]
  11. Dopazo J., Sobrino F., Palma E. L., Domingo E., Moya A. 1988; VP1 protein gene of foot-and-mouth disease virus: a quasispecies model of molecular evoltuion. Proceedings of the National Academy of Sciences, U,. S,. A. 85:6811–6815
    [Google Scholar]
  12. Dopazo J., Rodrigo M. J., Rodríguez A., Sáiz J. C., Sobrino F. 1993a; Aphthovirus evolution. In Molecular Evolution of Viruses Edited by Gibbs A., Calisher C. H. Cambridge University Press; (in press)
    [Google Scholar]
  13. Dopazo J., Rodriguez A., Sáiz J. C., Sobrino F. 1993b; Design of primers for PCR amplification of highly variable genomes. Computer Applications in the Biosciences 9:123–125
    [Google Scholar]
  14. Efron B. 1982; The jackknife, the bootstrap and other resampling plans. SIAMPhiladelphia
    [Google Scholar]
  15. Feigelstock D., Mateu M. G., Piccone M. E., De Simone F., Brocchi E., Domingo E., Palma E. L. 1992; Extensive antigenic diversification of foot-and-mouth disease virus by amino acid substitutions outside the major antigenic site. Journal of General Virology 73:3307–3311
    [Google Scholar]
  16. Felsenstein J. 1985; Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39:783–791
    [Google Scholar]
  17. Gonzalez M., Mateu M. G., Martínez M. A., Carrillo C., Sobrino F. 1992; Comparison of capsid protein VP1 of the viruses used for the production and challenge of foot-and-mouth disease vaccines in Spain. Vaccine 10:732–734
    [Google Scholar]
  18. Jensen M. J., Moore D. M. 1993; Phenotypic and functional characterization of mouse attenuated and virulent variants of foot and mouth disease virus type O1 Campos. Virology 193:604–613
    [Google Scholar]
  19. King A. M. Q., Underwood B. O., McCahon D., Newman J. W., Brown F. 1981; Biochemical identification of the viruses causing the 1981 outbreak of foot-and-mouth disease virus in U.K. Nature, London 293:479–480
    [Google Scholar]
  20. Kitson J. D. A., McCahon D., Belsham G. J. 1990; Sequence analysis of monoclonal antibody resistant mutants of type O foot-and-mouth disease virus: evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites. Virology 179:26–34
    [Google Scholar]
  21. Knowles N. J., Marquardt O., Samuel A. R. 1988; Antigenic and molecular characterization of isolates from recent outbreaks of foot-and-mouth disease virus in the Federal Republic of Germany. Report of the Session of the Research Group of the Standing Technical Committee of the European Commission for the Control of Foot-and-mouth Disease, Prague, Czechoslovakia 1988 pp 149–155 Rome: FAO;
    [Google Scholar]
  22. Krebs O., Berger H.-G, Marquardt O. 1991a; The capsid protein-encoding region of foot-and-mouth disease virus O2 Brescia. Archives of Virology 120:135–143
    [Google Scholar]
  23. Krebs O., Berger H.-G., Niedbalski W., Marquardt O. 1991b; Foot-and-mouth disease virus O1 Lombardy is biochemically related to O2 isolates. Virus Genes 5:255–266
    [Google Scholar]
  24. Kurz C., Forss S., Kupper H., Strohmaier K., Schaller H. 1981; Nucleotide sequence and corresponding amino acid sequence of the gene for the major antigen of foot-and-mouth disease virus. Nucleic Acids Research 9:1919–1931
    [Google Scholar]
  25. Laor O., Torgersen H., Yadin H., Becker Y. 1992; Detection of FMDV RNA amplified by the polymerase chain reaction (PCR). Journal of Virological Methods 36:197–208
    [Google Scholar]
  26. Makoff A., Paynter C., Rowlands D., Boothroyd J. 1982; Comparison of the amino acid sequence of the major immunogen from three serotypes of foot-and-mouth disease virus. Nucleic Acids Research 10:8285–8295
    [Google Scholar]
  27. Martínez M. A., Dopazo J., Hernandez J., Mateu M. G., Sobrino F., Domingo E., Knowles N. J. 1992; Evolution of the capsid protein genes of foot-and-mouth disease virus: antigenic variation without accumulation of amino acid substitutions over six decades. Journal of Virology 66:3557–3565
    [Google Scholar]
  28. Meyer R. F., Brown C. C., House C., House J. A., Molitor T. W. 1991; Rapid and sensitive detection of foot-and-mouth disease virus in tissues by enzymatic RNA amplification of the polymerase gene. Journal of Virological Methods 34:161–172
    [Google Scholar]
  29. Nei M., Gojobori T. 1986; Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Molecular Biology and Evolution 3:418–426
    [Google Scholar]
  30. Palmenberg A. 1989; Sequence alignments of picornaviral capsid proteins. In Molecular Aspects of Picornaviral Infection and Detection pp 211–241 Edited by Semler B. L., Ehrenfeld E. Washington, D.C.: American Society for Microbiology;
    [Google Scholar]
  31. Pereira H. G. 1981; Foot-and-mouth disease. In Virus Disease of Food Animals vol. 2 pp 333–363 Edited by Gibbs E. P. J. New York: Academic Press;
    [Google Scholar]
  32. Rieder Rojas E., Carrillo E., Schiappacassi M., Campos R. 1992; Modification of foot-and-mouth disease virus O1 Caseros after serial passages in the presence of antiviral polyclonal sera. Journal of Virology 66:3368–3372
    [Google Scholar]
  33. Rodríguez A., Martínez-Salas E., Dopazo J., Davila M., Sáiz J. C., Sobrino F. 1992; Primer design for specific diagnosis by PCR of highly variable RNA viruses: typing of foot-and-mouth disease virus. Virology 189:363–367
    [Google Scholar]
  34. Saitou N., Nei M. 1987; The neighbour-joining method: a new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4:406–425
    [Google Scholar]
  35. Sáiz J. C., Gonzalez M. J., Borca M. V., Sobrino F., Moore D. M. 1991; Identification of neutralizing antigenic sites on VP1 and VP2 of type A5 foot-and-mouth disease virus defined by neutralization resistant variants. Journal of Virology 65:2518–2524
    [Google Scholar]
  36. Sokal R. R., Rohlf F. J. 1981Biometry New York: Freeman;
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