1887

Abstract

The nucleotide sequence of feline panleukopenia virus (FPV) strain 193 was determined and compared with the sequence of canine parvovirus (CPV) strain N and partial sequences of FPV strain Carl and CPV strain b. Base differences were identified at 115 positions in these 5·1 kb genomes and predicted amino acid differences occurred at 40 positions. The two overlapping capsid protein genes contained almost twice as many base differences as the single non-structural protein gene (49 compared to 26) and about the same ratio was calculated for predicted amino acid differences (27 compared to 13). The 27 variant amino acids in the capsid proteins were clustered at three sites in the primary sequence, whereas 10 of the 13 variant amino acids in the non-structural protein occurred in the 130 C-terminal amino acids. The two FPV strains differed consistently from the two CPV strains at 31 bases: 12 base changes in the capsid protein genes resulted in six amino acid changes, six base changes in the nonstructural protein gene resulted in three amino acid changes, and 13 base changes occurred in the noncoding sequence.

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1990-11-01
2024-04-27
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References

  1. Anton I. A., Lane D. P. 1986; Nonstructural protein 1 of parvoviruses: homology to purine nucleotide using proteins and early proteins of papovaviruses. Nucleic Acids Research 14:7813
    [Google Scholar]
  2. Antonietti J. P., Sahli R. P., Beard P., Hirt B. 1988; Characterization of the cell type-specific determinant in the genome of minute virus of mice. Journal of Virology 62:552–557
    [Google Scholar]
  3. Astell C. R., Gardiner E. M., Tattersall P. 1986; DNA sequence of the lymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain. Journal of Virology 57:656–669
    [Google Scholar]
  4. Astell C. R., Mol C. D., Anderson W. F. 1987; Structural and functional homology of parvovirus and papovavirus polypeptides. Journal of General Virology 68:885–893
    [Google Scholar]
  5. Bensimhon M., Gabarro-Arpa J., Ehrlich R., Reiss C. 1983; Physical characteristics in eucaryotic promoters. Nucleic Acids Research 11:4521–4540
    [Google Scholar]
  6. Carlson J., Rushlow K., Maxwell I., Maxwell F., Winston S., Hahn W. 1985; Cloning and sequence of DNA encoding structural proteins of the autonomous parvovirus feline panleukopenia virus. Journal of Virology 55:574–582
    [Google Scholar]
  7. Cotmore S. F., Tattersall P. 1986; Organization of nonstructural genes of the autonomous parvovirus minute virus of mice. Journal of Virology 58:724–732
    [Google Scholar]
  8. Cotmore S. F., Sturzenbecker L. J., Tattersall P. 1983; The autonomous parvovirus MVM encodes two nonstructural proteins in addition to its capsid polypeptides. Virology 129:333–343
    [Google Scholar]
  9. Gardiner E. M., Tattersall P. 1988a; Evidence that developmentally regulated control of gene expression by a parvoviral allotropic determinant is particle mediated. Journal of Virology 62:1713–1722
    [Google Scholar]
  10. Gardiner E. M., Tattersall P. 1988b; Mapping of the fibrotropic and lymphotropic host range determinants of the parvovirus minute virus of mice. Journal of Virology 62:2605–2613
    [Google Scholar]
  11. Hirt B. 1967; Selective extraction of polyoma DNA from infected cell cultures. Journal of Molecular Biology 26:365–369
    [Google Scholar]
  12. Jongeneel C. V., Sahli R., Mcmaster G. K., Hirt B. 1986; A precise map of splice junctions in the mRNAs of minute virus of mice, an autonomous parvovirus. Journal of Virology 59:564–573
    [Google Scholar]
  13. Lebovitz R. M., Roeder R. G. 1986; Parvovirus H-1 expression: mapping of the abundant cytoplasmic transcripts and identification of promoter sites and overlapping transcription units. Journal of Virology 58:271–280
    [Google Scholar]
  14. Lenghaus C., Mun T. K., Studdert M. J. 1985; Feline panleukopenia virus replicates in cells in which cellular DNA synthesis is blocked. Journal of Virology 53:345–349
    [Google Scholar]
  15. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning: A Laboratory Manual New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  16. Mengeling W. L., Ridpath J. F., Vorwald A. C. 1988; Size and antigenic comparisons among the structural proteins of selected autonomous parvoviruses. Journal of General Virology 69:825–837
    [Google Scholar]
  17. Messing J. 1983; New M13 vectors for cloning. Methods in Enzymology 101:20–78
    [Google Scholar]
  18. Morgan W. R., Ward D. C. 1986; Three splicing patterns are used to excise the small intron common to all minute virus of mice RNAs. Journal of Virology 60:1170–1174
    [Google Scholar]
  19. O’Reilly K. J., Whitaker A. M. 1969; The development of feline cell lines for the growth of feline infectious enteritis (panleucopaenia) virus. Journal of Hygiene 67:115–124
    [Google Scholar]
  20. Paradiso P. R. 1984; Identification of multiple forms of the noncapsid parvovirus protein NCVP1 in H-1 parvovirus-infected cells. Journal of Virology 52:82–87
    [Google Scholar]
  21. Parrish C. R., Carmichael L. E. 1986; Characterization and recombination mapping of an antigenic and host range mutation of canine parvovirus. Virology 148:121–132
    [Google Scholar]
  22. Parrish C. R., Aquadro C. F., Carmichael L. E. 1988; Canine host range and a specific epitope map along with variant sequences in the capsid protein gene of canine parvovirus and related feline, mink, and raccoon parvoviruses. Virology 166:293–307
    [Google Scholar]
  23. Pintel D., Dadachanji D., Astell C. R., Ward D. C. 1983; The genome of minute virus of mice, an autonomous parvovirus, encodes two overlapping transcription units. Nucleic Acids Research 11:1019–1038
    [Google Scholar]
  24. Reed A. P., Jones E. V., Miller T. J. 1988; Nucleotide sequence and genome organization of canine parvovirus. Journal of Virology 62:266–276
    [Google Scholar]
  25. Rhode S. L.III 1985; Nucleotide sequence of the coat protein gene of canine parvovirus. Journal of Virology 54:630–633
    [Google Scholar]
  26. Rhode S. L.III Paradiso P. R. 1983; Parvovirus genome: nucleotide sequence of H-1 and mapping of its genes by hybrid- arrested translation. Journal of Virology 45:173–184
    [Google Scholar]
  27. Rhode S. L.III Richard S. M. 1987; Characterization of the trans-activation-responsive element of the parvovirus H-1 P38 promoter. Journal of Virology 61:2807–2815
    [Google Scholar]
  28. Sahli R., Mcmaster G. K., Hirt B. 1985; DNA sequence comparison between two tissue-specific variants of the autonomous parvovirus, minute virus of mice. Nucleic Acids Research 13:3617–3633
    [Google Scholar]
  29. Sanger F., Nicklen S., Coulson A. R. 1977; DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences, U.S.A 74:5463–5467
    [Google Scholar]
  30. Siegl G., Bates R. C., Berns K. I., Carter B. J., Kelly D. C., Kurstak E., Tattersall P. 1985; Characteristics and taxonomy of Parvoviridae. Intervirology 23:61–73
    [Google Scholar]
  31. Spalholz B. A., Tattersall P. 1983; Interaction of minute virus of mice with differentiated cells: strain-dependent target cell specificity is mediated by intracellular factors. Journal of Virology 46:937–943
    [Google Scholar]
  32. Staden R. 1982a; An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences. Nucleic Acids Research 10:2951–2961
    [Google Scholar]
  33. Staden R. 1982b; Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing. Nucleic Acids Research 10:4731–4751
    [Google Scholar]
  34. Studdert M. J., Peterson J. E. 1973; Some properties of feline panleukopenia virus. Archiv für die gesamte Virusforschung 42:346–354
    [Google Scholar]
  35. Wickens M., Stephenson P. 1984; Role of the conserved AAUAAA sequence: four AAUAAA point mutations prevent messenger RNA 3′ end formation. Science 226:1045–1051
    [Google Scholar]
  36. Yanisch-Perron C., Vieira J., Messing J. 1985; Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors. Gene 33:103–119
    [Google Scholar]
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