1887

Abstract

Summary

Alcelaphine herpesvirus type 1 (AHV-1) is a causative agent of the fatal lymphoproliferative disease malignant catarrhal fever in deer and cattle. The genomes of the attenuated WC11 isolate and the virulent C500 isolate have been studied. The genome of WC 11 comprises a region of unique DNA of approximately 130 kbp, which has a G + C content of 50%, and approximately 30 kbp of additional tandem direct repeat sequences with a G + C content of 72 %. WC11 possesses a major repeat sequence of 950 bp interspersed with a small number of related sequences of different length; these sequences are probably terminal in location. DNA from the C500 isolate has a similar restriction profile to that of WC11 in the unique region, but only one repeat sequence of 1050 bp is present. We propose, on the basis of biological and structural properties, that AHV-1 be included within the group of herpes viruses of which herpesvirus ateles is the prototype.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-70-5-1141
1989-05-01
2024-12-06
Loading full text...

Full text loading...

/deliver/fulltext/jgv/70/5/JV0700051141.html?itemId=/content/journal/jgv/10.1099/0022-1317-70-5-1141&mimeType=html&fmt=ahah

References

  1. Carle G. F., Olson M. V. 1984; Separation of chromosomal DNA molecules from yeast by orthogonal-field-alteration gel electrophoresis. Nucleic Acids Research 12:5647–5664
    [Google Scholar]
  2. Cohrs R., Rouhandeh H. 1987; Characterization of the genome of Herpesvirus sylvilagus . Intervirology 28:181–184
    [Google Scholar]
  3. Feinberg A. P., Vogelstein B. 1983; A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Analytical Biochemistry 132:6–13
    [Google Scholar]
  4. Feinberc A. P., Vogelstein B. 1984; Addendum: a technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Analytical Biochemistry 137:266–267
    [Google Scholar]
  5. Fleckenstein B., Mulder C. 1980; Molecular biological aspects of Herpesvirus saimiri and Herpesvirus ateles . In Viral Oncology799–812 Klein G. New York: Raven Press;
    [Google Scholar]
  6. Fleckenstein B., Bornkamm G. W., Ludwig H. 1975; Repetitive sequences incomplete and defective genomes of Herpesvirus saimiri . Journal of Virology 15:398–406
    [Google Scholar]
  7. Fleckenstein B., Bornkamm G. W., Mulder C., Werner F.-J., Daniel M. D., Falk L. A., Delius H. 1978; Herpesvirus ateles DNA and its homology with Herpesvirus saimiri nucleic acid. Journal of Virology 25:361–373
    [Google Scholar]
  8. Fuchs P. G., Roger R., Pfister H., Fleckenstein B. 1985; Genome organization of Herpesvirus aotus type 2. Journal of Virology 53:13–18
    [Google Scholar]
  9. Goodheart C. R., Plummer G. 1975; The densities of herpesviral DNAs. Progress in Medical Virology 19:324–352
    [Google Scholar]
  10. Grosveld F. G., Dahl H. H., De Boer E., Flavell R. A. 1981; Isolation of β-globin-related genes from a human cosniid library. Gene 13:227–237
    [Google Scholar]
  11. Herring A. J., Inglis N. F., Ojeh C. K., Snodgrass D. R., Menzies J. D. 1982; Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamide gels. Journal of Clinical Microbiology 16:473–477
    [Google Scholar]
  12. Herring A., Reid H., Inglis N., Pow I. 1989; Immunoblotting analysis of the reaction of wildebeest, sheep and cattle sera with the structural antigens of Alcelaphine herpesvirus-l. Veterinary Microbiology (in press)
    [Google Scholar]
  13. Hirt B. 1967; Selective extraction of polyoma DNA from infected mouse cell cultures. Journal of Molecular Biology 26:365–369
    [Google Scholar]
  14. Honess R. W. 1984; Herpes simplex and ‘the herpes complex’: diverse observations and a unifying hypothesis. Journal of General Virology 65:2077–2107
    [Google Scholar]
  15. Hunt R. D., Billups L. H. 1979; Wildebeest-associated malignant catarrhal fever in Africa: a neoplastic disease of cattle caused by an oncogenic herpesvirus?. Comparative Immunology and Microbiology of Infectious Diseases 2:275–283
    [Google Scholar]
  16. Jacoby R. O., Reid H. W., Buxton D., Pow I. 1988; Transmission of wildebeest-associated and sheep-associated malignant catarrhal fever to hamster, rats and guinea-pigs. Journal of Comparative Pathology 98:91–98
    [Google Scholar]
  17. Kaiser K., Murray N. E. 1985; The use of phage lambda replacement vectors in the construction of representative genomic DNA libraries. In DNA Cloning 11–47 Glover D. M. Oxford: IRL Press;
    [Google Scholar]
  18. Kramp W. J., Medveczky P., Mulder C., Hinze H. C., Sullivan J. L. 1985; Herpesvirus sylvilagus infects bothB and T lymphocytes in vivo . Journal of Virology 56:60–65
    [Google Scholar]
  19. Ludwig H. 1983; Bovine herpesviruses. In The Herpesviruses 2135–214 Roizman B. New York & London: Plenum Press;
    [Google Scholar]
  20. McClenaghan M., Herring A. J., Aitken I. D. 1984; Comparison of Chlamydia psittaci isolates by DNA restriction endonuclease analysis. Infection and Immunity 45:384–394
    [Google Scholar]
  21. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning: A Laboratory Manual New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  22. Messing J. 1983; New M13 vectors for cloning. Methods in Enzymology 101:20–78
    [Google Scholar]
  23. Murray N. E., Brammar W. J., Murray K. 1977; Lambdoid phages that simplify the recovery of in vitro recombinants. Molecular and General Genetics 150:53–61
    [Google Scholar]
  24. Mushi E. Z., Karstad L., Jessett D. M. 1980; Isolation of bovine malignant catarrhal fever virus from ocular and nasal secretions of wildebeest calves. Research in Veterinary Science 29:168–171
    [Google Scholar]
  25. Ortaldo J. R., Neubauer R. H., Blanca I., Rabin H. 1985; Cytotoxic activity of normal and herpesvirus saimiri-transformed nonhuman primate cells. Cellular Immunology 95:349–357
    [Google Scholar]
  26. Osorio F. A., Reed D. E., Van Der Maaten M. J., Metz C. A. 1985; Comparison of the herpesviruses of cattle by DNA restriction endonuclease analysis and serologic analysis. American Journal of Veterinary Research 10:2104–2109
    [Google Scholar]
  27. Patel J. R., Edington N. 1980; The detection of the herpesvirus of bovine malignant catarrhal fever in rabbit lymphocytes in vivo and in vitro . Journal of General Virology 48:437–444
    [Google Scholar]
  28. Patel J. R., Edington N. 1981; The detection and behaviour of the herpesvirus of malignant catarrhal fever in bovine lymphocytes. Archives of Virology 68:321–326
    [Google Scholar]
  29. Plowright W. 1967; Malignant catarrhal fever in East Africa. III. Neutralizing antibody in free-living wildebeest. Research in Veterinary Science 8:129–136
    [Google Scholar]
  30. Plowright W. 1968; Malignant catarrhal fever. Journal of the American Veterinary Medical Association 152:795–804
    [Google Scholar]
  31. Plowright W. 1982; Malignant catarrhal fever virus: a lymphotropic herpesvirus of ruminants. In Latent Herpesvirus Infections in Veterinary Medicine279–305 Wittman G., Gaskell R., Ryiha H. Boston & The Hague: Martinus Nijhoff;
    [Google Scholar]
  32. Plowright W., Ferris R. D., Scott G. R. 1960; Blue wildebeest and the aetiological agent of bovine malignant catarrhal fever. Nature, London 188:1167–1169
    [Google Scholar]
  33. Plowright W., Macadam R. F., Armstrong J. A. 1963; Growth and characterization of the virus of bovine malignant catarrhal fever in East Africa. Journal of General Microbiology 39:253–266
    [Google Scholar]
  34. Plowright W., Herniman K. A. J., Jessett D. M., Kalunda M., Rampton C. S. 1975; Immunisation of cattle against the herpesvirus of malignant catarrhal fever; failure of inactivated vaccines with adjuvant. Research in Veterinary Science 19:159–166
    [Google Scholar]
  35. Reid H. W., Buxton D. 1984; Malignant catarrhal fever of deer. Proceedings of the Royal Society of Edinburgh 82B:261–273
    [Google Scholar]
  36. Reid H. W., Jacoby R. O., Pow I., Buxton D. 1984; Culture of large granular lymphocytes from rats with a herpesvirus-associated lymphoproliferative condition. Immunobiology 167:192
    [Google Scholar]
  37. Rigby P. W. J., Dieckmann M., Rhodes C., Berg P. 1977; Labelling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. Journal of Molecular Biology 113:237–251
    [Google Scholar]
  38. Roizman B. 1982; The family Herpesviridae: general description, taxonomy and classification. In The Herpesviruses 11–23 Roizman B. New York & London: Plenum Press;
    [Google Scholar]
  39. Rossiter P. B. 1981; Antibodies to malignant catarrhal fever virus in sheep sera. Journal of Comparative Pathology 91:303–311
    [Google Scholar]
  40. Schildkraut C. L., Marmur J., Doty P. 1962; Determination of the base composition of deoxyribonucleic acid from its buoyant density in CsCl. Journal of Molecular Biology 4:430–443
    [Google Scholar]
  41. Smith G. E., Summers M. D. 1980; The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl paper. Analytical Biochemistry 109:123–129
    [Google Scholar]
  42. Stamminger T., Honess R. W., Young D. F., Bodemer W., Blair E. D., Fleckenstein B. 1987; Organization of terminal reiterations in the virion DNA of herpesvirus saimiri. Journal of General Virology 68:1049–1066
    [Google Scholar]
  43. Storz J. 1976; Virologic studies on cattle with naturally occurring and experimentally induced malignant catarrhal fever. American Journal of Veterinary Research 37:875–878
    [Google Scholar]
  44. Touring R. W. J., Sanders J. P. M., Borst P. 1975; A freeze-squeeze method for recovering long DNA from agarose gels. Analytical Biochemistry 66:213–220
    [Google Scholar]
/content/journal/jgv/10.1099/0022-1317-70-5-1141
Loading
/content/journal/jgv/10.1099/0022-1317-70-5-1141
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error