1887

Abstract

Summary

A number of CD4 T cell lines were compared for their ability to act as target cells for human immunodeficiency virus (HIV) infection in syncytium- and plaque-forming assays. MT-4 and C8166 cells were the most sensitive indicator cells for HIV- and simian immunodeficiency virus (SIV)-induced cytopathic effects, and gave rise to macroscopic (MT-4) and microscopic (C8166) plaques. The MT-4 plaque assay was evaluated for the measurement of HIV- and SIV-neutralizing antibodies.

Keyword(s): HIV , neutralization , plaque assays and SIV
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/content/journal/jgv/10.1099/0022-1317-70-12-3327
1989-12-01
2019-10-20
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-70-12-3327
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