1887

Abstract

Summary

Human rotaviruses containing rearranged genomes were found to package up to 1800 additional base pairs in virus particles. The viruses compared were indistinguishable in respect of their particle diameters and their apparent S values. Particles containing rearranged genomes were found to be of a higher density than rotavirus particles containing a standard genome as determined by equilibrium density ultracentrifugation. The increase in density was directly proportional to the number of additionally packaged base pairs.

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1987-11-01
2022-01-21
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References

  1. Allen A. M., Desselberger U. 1985; Reassortment of human rotaviruses carrying rearranged genomes with bovine rotaviruses. Journal of General Virology 66:2703–2714
    [Google Scholar]
  2. Bellinzoni R. C., Mattion N., Burrone O., Gonzalez A., La Torre J., Scodeller E. A. 1987; Isolation of group A swine rotaviruses displaying atypical electropherotypes. Journal of Clinical Microbiology 25:952–954
    [Google Scholar]
  3. Besselaar T. G., Rosenblatt A., Kidd A. H. 1986; Atypical rotavirus from South African neonates. Archives of Virology 87:327–330
    [Google Scholar]
  4. Bridger J. C., Pedley S., Mccrae M. A. 1986; Group C rotaviruses in humans. Journal of Clinical Microbiology 23:760–763
    [Google Scholar]
  5. Eaton B. T., Gould A. R. 1987; Isolation and characterization of orbi virus genotypic variants. Virus Research 6:363–382
    [Google Scholar]
  6. Flossdorf J. 1980; Erweiterte Möglichkeiten in der analytischen Ultrazentrifugation durch Verwendung eines neuartigen Kollimators. Makromolekulare Chemie 181:715–724
    [Google Scholar]
  7. Follett E. A. C., Sanders R. C., Beards G. M., Hundley F., Desselberger U. 1984; Molecular epidemiology of human rotaviruses. Analysis of outbreaks of acute gastroenteritis in Glasgow and the west of Scotland 1981/82 and 1982/83. Journal of Hygiene 92:209–222
    [Google Scholar]
  8. Gomatos P. J., Tamm I. 1963; The secondary structure of reovirus RNA. Proceedings of the National Academy of Sciences, U.S.A 49:707–714
    [Google Scholar]
  9. Graham A., Kudesia G., Allen A. M., Desselberger U. 1987; Reassortment of human rotavirus possessing genome rearrangements with bovine rotavirus: evidence for host cell selection. Journal of General Virology 68:115–122
    [Google Scholar]
  10. Holmes I. H. 1983; Rotaviruses. In The Reoviridae pp. 359–423 Joklik W. K. Edited by New York and London: Plenum Press;
    [Google Scholar]
  11. Hundley F., Biryahwaho B., Gow M., Desselberger U. 1985; Genome rearrangements of bovine rotavirus after serial passage at high multiplicity of infection. Virology 143:88–103
    [Google Scholar]
  12. Hundley F., Mcintyre M., Clark B., Beards G., Wood D., Chrystie I., Desselberger U. 1987; Heterogeneity of genome rearrangements in rotaviruses isolated from a chronically infected immunodeficient child. Journal of Virology in press
    [Google Scholar]
  13. Mccrae M. A. 1985; Double-stranded RNA viruses. In Virology-A Practical Approach pp. 151–168 Mahy B. W. J. Edited by Oxford and Washington, D.C: IRL Press;
    [Google Scholar]
  14. Mcnulty M. S. 1979; Morphology and chemical composition of rotaviruses. In Viral Enteritis in Humans and Animals pp. 111–140 Bricout F., Scherrer R. Edited by Paris: Editions INSERM;
    [Google Scholar]
  15. Pedley S., Hundley F., Chrystie I., Mccrae M. A., Desselberger U. 1984; The genomes of rotaviruses isolated from chronically infected immunodeficient children. Journal of General Virology 65:1141–1150
    [Google Scholar]
  16. Pedley S., Bridger J. C., Chasey D., Mccrae M. A. 1986; Definition of two new groups of atypical rotaviruses. Journal of General Virology 67:131–137
    [Google Scholar]
  17. Pocock D. H. 1987; Isolation and characterization of two group A rotaviruses with unusual genome profiles. Journal of General Virology 68:653–660
    [Google Scholar]
  18. Rappold W. 1986 Entwicklung einer Fluoreszenzoptik für die analytische Ultrazentrifuge und ihre Anwendmg auf biophysikalische Fragestellungen Ph.D. thesis University of Diisseldorf:
    [Google Scholar]
  19. Rixon F., Taylor P., Desselberger U. 1984; Rotavirus RNA segments sized by electron microscopy. Journal of General Virology 65:233–239
    [Google Scholar]
  20. Rodger S. M., Schnagl R. D., Holmes I. H. 1975; Biochemical and biophysical characteristics of diarrhea viruses of human and calf origin. Journal of Virology 16:1229–1235
    [Google Scholar]
  21. Schachman H. K. 1959 Ultracentrifugation in Biochemistry New York & London: Academic Press;
    [Google Scholar]
  22. Scott G. S., Mccrae M. A., Pocock D. 1986; Molecular analysis of a bovine rotavirus with a gross genomic abnormality. Abstracts, International Symposium on Double-Stranded RNA Viruses, Oxford
    [Google Scholar]
  23. Tam J. S., Szymanski M. T., Middleton P. J., Petric M. 1976; Studies on the particles of infantile gastroenteritis virus (orbivirus group). Intervirology 1:181–191
    [Google Scholar]
  24. Thouless M. E., Digiacomo R. F., Neuman D. S. 1986; Isolation of two lapine rotaviruses: characterization of their subgroup, serotype and RNA electropherotypes. Archives of Virology 89:161–170
    [Google Scholar]
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