1887

Abstract

SUMMARY

The genomes of influenza C viruses isolated from pigs in Beijing, China during 1981/82 and of human influenza C virus strains isolated between 1947 and 1981 were analysed by comparison of RNA migration patterns on gels and by two-dimensional oligonucleotide (ON) mapping. The genomes of the pig isolates were closely related to one another, though in part distinguishable by point mutations. They were similar to but more distantly related to the genomes of human influenza C viruses. The genome of the C/pig/Beijing/10/81 isolate differed from that of the C/pig/Beijing/32/81 isolate obtained on the same day at the same place by a number of mutations which were all located in RNA segments 1 and 2 as shown by ON mapping. This result suggests that the two isolates are genetically related by a reassortment event which is likely to have occurred in nature. The question whether or not pigs are a natural reservoir for human influenza C viruses cannot be answered at present.

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1984-11-01
2021-10-26
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References

  1. Air G. M., Acompans R. W. 1983; Influenza B and influenza C viruses. In Genetics of Influenza Viruses pp 280–304 Edited by Palese P., Kingsbury D. W. Wien & New York: Springer-Verlag;
    [Google Scholar]
  2. Chakraverty P. 1978; Antigenic relationship between influenza C viruses. Archives of Virology 58:341–348
    [Google Scholar]
  3. Desselberger U., Nakajima K., Alfino P., Pedersen F. S., Haseltine W., Hannoun C., Palese P. 1978; Biochemical evidence that ‘new’ influenza virus strains in nature may arise by recombination (reassortment). Proceedings of the National Academy of Sciences, U. S. A 75:3341–3345
    [Google Scholar]
  4. Desselberger U., Racaniello V. R., Zazra J. J., Palese P. 1980; The 3′ and 5′ terminal sequences of influenza A, B, and C virus RNA segments are highly conserved and show partial inverted complementarity. Gene 8:315–328
    [Google Scholar]
  5. Elliott R. M., Guo Y. J., Desselberger U. 1984; Polypeptide synthesis in MDCK cells infected with human and pig influenza C viruses. Journal of General Virology 65:1873–1880
    [Google Scholar]
  6. Francis T., Quilligan J. J., Minuse E. 1950; Identification of another epidemic respiratory disease. Science 112:495–497
    [Google Scholar]
  7. Guo Y. J., Jin F. G., Wang P., Wang M., Zhu J. M. 1983a; Isolation of influenza C virus from pigs and experimental infection of pigs with influenza C virus. Journal of General Virology 64:177–182
    [Google Scholar]
  8. Guo Y. J., Wang M., Jin F. G., Wang P., Zhu J. M. 1983b; Influenza ecology in China. In The Origin of Pandemic Influenza Viruses pp 211–220 Edited by Laver W. G. New York: Elsevier;
    [Google Scholar]
  9. Homma M., Ohyama S., Katagiri S. 1982; Age distribution of the antibody to type C influenza virus. Microbiology and Immunology 26:639–642
    [Google Scholar]
  10. Katagiri S., Ohizumi A., Homma M. 1983; An outbreak of type C influenza in a children’s home. Journal of Infectious Diseases 148:51–56
    [Google Scholar]
  11. Kendal A. P. 1975; A comparison of ‘influenza C’ with prototype myxoviruses: receptor-destroying activity (neuraminidase) and structural polypeptides. Virology 65:87–99
    [Google Scholar]
  12. Krystal M., Buonagurio D., Young J. F., Palese P. 1983a; Sequential mutations in the NS genes of influenza virus field strains. Journal of Virology 45:547–554
    [Google Scholar]
  13. Krystal M., Young J. F., Palese P., Wilson I. A., Skehel J. J., Wiley D. C. 1983b; Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antibody domains. Proceedings of the National Academy of Sciences, U. S. A 80:4527–4531
    [Google Scholar]
  14. Lamb R. A. 1983; The influenza virus RNA segments and their proteins. In Genetics of Influenza Viruses pp 21–69 Edited by Palese P., Kingsbury D. W. Wien & New York: Springer-Verlag;
    [Google Scholar]
  15. Loening U. E. 1967; The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. Biochemical Journal 102:251–257
    [Google Scholar]
  16. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning: A Laboratory Handbook pp 164–468 New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  17. Meier-Ewert H., Compans R. W., Bishop D. H. L., Herrler G. 1978; Molecular analysis of influenza C virus. In Negative Strand Viruses and the Host Cell pp 127–133 Edited by Mahy B. W. J., Barry R. D. New York: Academic Press;
    [Google Scholar]
  18. Meier-Ewert H., Petri T., Bishop D. H. L. 1981; Oligonucleotide fingerprint analysis of influenza C virion RNA recovered from five different isolates. Archives of Virology 67:141–147
    [Google Scholar]
  19. Nakada S., Creager R. S., Krystal M., Aaronson R. P., Palese P. 1984; Influenza C virus hemagglutinin: comparison with influenza A and B virus hemagglutinins. Journal of Virology 50:118–124
    [Google Scholar]
  20. Nakajima K., Desselberger U., Palese P. 1978; Recent human influenza A viruses are closely related genetically to strains isolated in 1950. Nature, London 274:334–339
    [Google Scholar]
  21. Nerome K., Ishida M., Nakayama M. 1976; Absence of neuraminidase from influenza C virus. Archives of Virology 50:241–244
    [Google Scholar]
  22. O’Callaghan R. J., Godh R. S., Labat D. D. 1980; Human antibody to influenza C virus: its age-related distribution and distinction from receptor analogs. Infection and Immunity 30:500–505
    [Google Scholar]
  23. Palese P., Schulman J. L. 1976; Differences in RNA patterns of influenza A viruses. Journal of Virology 17:876–884
    [Google Scholar]
  24. Palese P., Racaniello V. R., Desselberger U., Young J., Baez M. 1980; Genetic structure and genetic varation of influenza viruses. Philosophical Transactions of the Royal Society of London, series B 288:299–305
    [Google Scholar]
  25. Palese P., Elliott R. M., Baez M. L., Zazra J. J., Young J. F. 1981; Genome diversity among influenza A, B and C viruses and genetic structure of RNA 7 and RNA 8 of influenza A viruses. In Genetic Variation Among Influenza Viruses pp 127–140 Edited by Nayak D. P. New York: Academic Press;
    [Google Scholar]
  26. Peacock A. C., Dingman C. W. 1968; Molecular weight estimation and separation of ribonucleic acid by electrophoresis in agarose-acrylamide composite gels. Biochemistry 1:668–674
    [Google Scholar]
  27. Pedersen F. S., Haseltine W. A. 1980; A micromethod for detailed characterization of high molecular weight RNA. Methods in Enzymology 65:680–687
    [Google Scholar]
  28. Pfeifer J. B., Compans R. W. 1984; Structure of the influenza C glycoprotein gene as determined from cloned DNA. Virus Research 1:281–296
    [Google Scholar]
  29. Quilligan J. J., Minuse E., Francis T. 1954; Type C influenza virus. II. Intranasal inoculation of human individuals. Journal of Laboratory and Clinical Medicine 43:43–47
    [Google Scholar]
  30. Racaniello V. R., Palese P. 1979; Isolation of influenza virus recombinants. Journal of Virology 32:1006–1014
    [Google Scholar]
  31. Ritchey M. B., Palese P., Kilbourne E. D. 1976; The RNAs of influenza A, B and C viruses. Journal of Virology 18:738–744
    [Google Scholar]
  32. Taylor R. M. 1949; Studies on survival of influenza virus between epidemics and antigenic variants of the virus. American Journal of Public Health 39:171–178
    [Google Scholar]
  33. Taylor R. M. 1951; A further note on 1233 (‘influenza C’) virus. Archiv für die gesamte Virusforschung 4:485–500
    [Google Scholar]
  34. Whitton J. L., Hundley F., O’Donnell B., Desselberger U. 1983; Silver staining of nucleic acids. Applications in virus research and in diagnostic virology. Journal of Virological Methods 7:185–198
    [Google Scholar]
  35. Young J. F., Palese P. 1979; Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 viruses. Proceedings of the National Academy of Sciences, U. S. A 76:6547–6551
    [Google Scholar]
  36. Young J. F., Desselberger U., Palese P. 1979; Evolution of human influenza A viruses in nature: sequential mutations in the genomes of new H1N1 isolates. Cell 18:73–83
    [Google Scholar]
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