1887

Abstract

Summary

Passive transfer of monoclonal antibodies specific for herpes simplex virus type 1 (HSV-1) glycoproteins gC or gD resulted in the generation of highly potent HSV-specific and H-2-restricted primary cytotoxic T-lymphocytes (CTL) in the lymph nodes of recipients provided they were injected at 12 h post-infection. When the same antibody was injected at 3 h before HSV infection, the recipients failed to generate primary anti-HSV CTL. Rather, lymph node cells from such donors proved unsuitable for the initiation of a secondary anti-HSV CTL response by restimulation.

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/content/journal/jgv/10.1099/0022-1317-64-9-2033
1983-09-01
2019-10-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-64-9-2033
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