1887

Abstract

Summary

Coronavirus JHM contains six major proteins, one of which, the 60000 mol. wt. nucleocapsid protein pp60, is phosphorylated. In JHM-infected cells ip 60K, the intracellular precursor to pp60 is also phosphorylated. Associated with purified JHM virions is a protein kinase which will phosphorylate pp60 and a variety of exogenous substrates . The enzyme has the characteristics of a cyclic nucleotide-independent protein kinase. Both the reaction and the enzyme activity transferred the γ-phosphate of ATP to serine residues on the nucleocapsid protein.

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/content/journal/jgv/10.1099/0022-1317-52-2-235
1981-02-01
2019-10-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-52-2-235
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