1887

Abstract

SUMMARY

Newly synthesized nuclear NP, M and NS proteins migrated from the nucleus over a period of several hours. Rates of transport were higher for NP than for M or NS and suggest that nuclear NP may play a role in multiplication.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-45-2-527
1979-11-01
2024-12-06
Loading full text...

Full text loading...

/deliver/fulltext/jgv/45/2/JV0450020527.html?itemId=/content/journal/jgv/10.1099/0022-1317-45-2-527&mimeType=html&fmt=ahah

References

  1. Bell D. 1974; DNA synthesis in ‘nuclear monolayers’ from BSC–1 cells infected with herpes virus. Nature, London 248:505–508
    [Google Scholar]
  2. Breitenfeld P. M., Schafer W. 1957; The formation of fowl plague virus antigens in infected cells, as studied with fluorescent antibodies. Virology 4:328–345
    [Google Scholar]
  3. Cook R. F., Avery R. J., Dimmock N. J. 1979; Differential distribution of influenza virus P proteins in nuclei of infected cells. FEMS Microbiology Letters (in the press)
    [Google Scholar]
  4. Dimmock N. J. 1969; New virus–specific antigens in cells infected with influenza virus. Virology 39:224–234
    [Google Scholar]
  5. Flawith J. W. F. 1979; Intracellular locations of influenza A virus proteins. Ph,. D. Thesis University of Warwick;
    [Google Scholar]
  6. Fraser K. B. 1967; Immunofluorescence of abortive and complete infections by influenza A virus in hamster BHK 21 cells and mouse L cells. Journal of General Virology 1:1–12
    [Google Scholar]
  7. Gregoriades A. 1973; The membrane protein of influenza virus: extraction from virus and infected cell with acid chloroform–methanol. Virology 54:369–383
    [Google Scholar]
  8. Hay J. A., Skehel J. J. 1975; Studies on the synthesis of influenza virus proteins. In Negative Strand Viruses II pp 635 Edited by Mahy J. B. W. Barry R. D. London: Academic Press;
    [Google Scholar]
  9. Hudson J. B., Dimmock N. J. 1977; The use of nuclear monolayers in the study of influenza virus–infected cells. FEMS Microbiology Letters 1:325–327
    [Google Scholar]
  10. Hudson J. B., Flawith J., Dimmock N. J. 1978; Early events in influenza virus infection. III. The formation of a nucleoplasmic ribonucleoprotein complex from the input virion. Virology 86:167–176
    [Google Scholar]
  11. Kelly D. C., Dimmock N. J. 1974; Fowl plague virus replication in mammalian cell–avian erythrocyte heterokaryons: studies concerning the actinomycin D and ultraviolet light sensitive phase in influenza virus replication. Virology 61:210–222
    [Google Scholar]
  12. Krug R. M., Etkind P. R. 1973; Cytoplasmic and nuclear virus–specified proteins in influenza–infected MDCK cells. Virology 56:334–348
    [Google Scholar]
  13. Krug F. M., Etkind P. R. 1975; Influenza virus–specific products in the nucleus and cytoplasm of infected cells. In Negative Strand Viruses II p 555 Edited by Mahy J. B. W., Barry R. D. London: Academic Press;
    [Google Scholar]
  14. Krug R. M., Soeiro R. 1975; Studies on the intranuclear localization of influenza virus specific proteins. Virology 64:378–387
    [Google Scholar]
  15. Lazarowitz S. G., Compans R. W., Choppin P. W. 1971; Influenza virus structural and non–structural proteins in infected cells and their plasma membranes. Virology 46:830–843
    [Google Scholar]
  16. Maeno K., Kilbourne E. D. 1970; Developmental sequence and intracellular sites of synthesis of three structural protein antigens of influenza A2 virus. Journal of Virology 5:153–164
    [Google Scholar]
  17. Minor P. D., Dimmock N. J. 1975; Inhibition of synthesis of influenza virus proteins: evidence for two host–cell–dependent steps during multiplication. Virology 67:114–123
    [Google Scholar]
  18. Morser M. J., Kennedy S. I. T., Burke D. C. 1973; Virus–specified polypeptides in cells infected with Semliki Forest virus. Journal of General Virology 21:19–29
    [Google Scholar]
  19. Oxford J. S., Schild G. C. 1975; Immunological studies with influenza virus matrix protein. In Negative Strand Viruses II p 611 Edited by Mahy J. B. W., Barry R. D. London: Academic Press;
    [Google Scholar]
  20. Stephenson J. R., Dimmock N. J. 1975; Early events in influenza virus multiplication. I. Location and fate of the input RNA. Virology 65:77–86
    [Google Scholar]
  21. Stephenson S. R., Hudson J. B., Dimmock N. J. 1978; Early events in influenza virus multiplication. II,. Penetration of virus into cells at 40 . Virology 86:264–271
    [Google Scholar]
  22. Studier R. W. 1973; Analysis of bacteriophage T7 RNAs and proteins on slab gels. Journal of Molecular Biology 79:237–248
    [Google Scholar]
  23. Taylor J. M., Hampson A. W., White D. O. 1969; The polypeptides of influenza virus. I. Cytoplasmic synthesis and nuclear accumulation. Virology 39:419–425
    [Google Scholar]
  24. Taylor J. M., Hampson A. W., Layton J. E., White D. O. 1970; The polypeptides of influenza virus. IV.An analysis of nuclear accumulation. Virology 42:744–752
    [Google Scholar]
  25. Tsai R. L., Green H. 1973; Rate of RNA synthesis in ghost monolayers obtained from fibroblasts preparing for division. Nature New Biology 243:168–169
    [Google Scholar]
/content/journal/jgv/10.1099/0022-1317-45-2-527
Loading
/content/journal/jgv/10.1099/0022-1317-45-2-527
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error