1887

Abstract

SUMMARY

The haemolysin of measles virus, either in the virion or in infected cells, is functionally and antigenically sensitive to acetone. Absorption of human sera with acetone-treated, measles virus-infected cells removes antibodies to all measles virus structural antigens except haemolysin. The antibody titres of absorbed sera give good correlation in HLI, neutralization and fluorescent antibody staining on unfixed infected cells.

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/content/journal/jgv/10.1099/0022-1317-44-2-541
1979-08-01
2024-04-26
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References

  1. Ehrnst A., Sundqvist K.-G. 1975; Polar appearance and non-ligand induced spreading of measles virus haemagglutinin at the surface of chronically infected cells. Cell 5:351–359
    [Google Scholar]
  2. Ehrnst A., Weiner L. P., Norrby E. 1974; Fluctuations and distribution of measles virus antigens in chronically infected cells. Nature, London 248:691
    [Google Scholar]
  3. Fraser K. B., Shirodaria P. V., Haire M. 1974; Enzyme treatment of unfixed cell cultures as a means of determining different specificities of IgM in multiple sclerosis and measles. Medical Microbiology and Immunobiology 160:221–230
    [Google Scholar]
  4. Fraser K. B., Gharpure M., Shirodaria P. V., Armstrong M. A., Moore A., Dermott E. 1978; Distribution and relationship of antigens of measles virus membrane complex in the infected cell and the nature of the haemolysin antigen. In Negative Strand Viruses and the Host Cell pp 771–780 Edited by Mahy B. W. J., Barry R. London: Academic Press;
    [Google Scholar]
  5. Fraser K. B., Armstrong M. A., Shirodaria P. V., Gharpure M. 1979; Affinity for measles virus anti-haemolysin of a residual immunoglobulin M in sera of some patients with multiple sclerosis. Clinical and Experimental Immunology (in the press)
    [Google Scholar]
  6. Gould E. A. 1974; Variants of measles virus. Medical Microbiology and Immunobiology 160:211–219
    [Google Scholar]
  7. Norrby E., Gollmar Y. 1972; Appearance and persistence of antibodies against different virus components after regular measles infections. Infection and Immunity 6:240–247
    [Google Scholar]
  8. Norrby E., Gollmar Y. 1975; Identification of measles virus-specific haemolysis-inhibiting antibodies separate from haemagglutination-inhibiting antibodies. Infection and Immunity it:231–239
    [Google Scholar]
  9. Shirodaria P. V., Dermott E., Gould E. A. 1976; Some characteristics of salt-dependent haemagglutinating measles viruses. Journal of General Virology 33:107–115
    [Google Scholar]
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