1887

Abstract

SUMMARY

A line of SV40-transformed mouse cells (SV/3T3-4E) was isolated and four clones were derived from this line. Spontaneous production of small amounts of infectious SV40 DNA was detected in the parental line and in three out of the four clones tested, although no synthesis of virions could be demonstrated. The yields of SV40 DNA were significantly enhanced following treatment of these cells with mitomycin C and infectious virus particles became detectable occasionally.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-41-1-201
1978-10-01
2021-10-19
Loading full text...

Full text loading...

/deliver/fulltext/jgv/41/1/JV0410010201.html?itemId=/content/journal/jgv/10.1099/0022-1317-41-1-201&mimeType=html&fmt=ahah

References

  1. Biczysko W., Solter D., Pienkowski M., Koprowski H. 1973; Interactions of early mouse embryos with oncogenic viruses – simian virus 40 and polyoma. I. Ultrastructural studies.. Journal of the National Cancer Institute 51:1945–1954
    [Google Scholar]
  2. Daya-Grosjean L., Benichou D., Monier R. 1975; Présence de DNA non intégré du virus Simien 40 dans des cellules non productrices transformées par ce virus.. Comptes Rendus de l’ Académie des Sciences, Paris 281:679–682
    [Google Scholar]
  3. Hirt B. 1967; Selective extraction of polyoma DNA from infected mouse cell cultures.. Journal of Molecular Biology 36:365–369
    [Google Scholar]
  4. Kaplan J. C., Wilbert S. M., Collins J. J., Rakusanova T., Zamansky O. B., Black P. H. 1975; Isolation of simian virus 40-transformed inbred hamster cell lines heterogeneous for virus induction by chemicals or radiation.. Virology 68:200–214
    [Google Scholar]
  5. Lavialle C. H., Suarez H. G., Morris A. G., Estrade S., Stevenet J., Cassingena R. 1976; Simian Virus 40-Chinese hamster kidney cell interaction. II. The semi-permissivity of the cell system.. Archives of Virology 50:137–146
    [Google Scholar]
  6. Lavialle C. H., Morris A. G., Suarez H. G., Estrade S., Stevenet J., Cassingena R. 1977; Simian virus 40-Chinese hamster kidney cell interaction. IV. Enhanced virus replication in infected cells upon treatment with mitomycin C.. Journal of General Virology 36:137–149
    [Google Scholar]
  7. Martin M. A., Khoury G. 1976; Integration of DNA tumor virus genomes.. Current Topics in Microbiology and Immunology 73:35–65
    [Google Scholar]
  8. Matsuya Y., Green H. 1969; Somatic cell hybrid between the established human line D 98 (presumptive HeLa) and 3T3.. Science 163:697–698
    [Google Scholar]
  9. Montagnier L., Macpherson I. 1964; Croissance sélective en gélose de cellules de hamster transformées par le virus du polyome.. Comptes Rendus de l’ Académie des Sciences, Paris 258:4171–4173
    [Google Scholar]
  10. Morris A. G., Lavialle C. H., Suarez H. G., Cassingena R. 1975; The induction of SV40-transformed Chinese hamster and mouse kidney cells by mitomycin C.. Intervirology 5:305–312
    [Google Scholar]
  11. Morris A. G., Lavialle C. H., Suarez H. G., Stevenet J., Estrade S., Cassingena R. 1977; Simian virus 40-Chinese hamster kidney cell interaction. III. Characteristics of chemical induction in a clone of virogenic transformed cells.. Journal of General Virology 36:123–135
    [Google Scholar]
  12. Prasad I., Zouzias D., Basilico C. 1976; State of the viral DNA in rat cells transformed by polyoma virus. I. Virus rescue and the presence of nonintegrated viral DNA.. Journal of Virology 18:436–444
    [Google Scholar]
  13. Rakusanova T., Kaplan I. C., Smales W. P., Black P. H. 1976; Excision of viral DNA from host cell DNA after induction of simian virus 40-transformed hamster cells.. Journal of Virology 19:279–285
    [Google Scholar]
  14. Watkins J. F. 1973; Studies on a virogenic clone of SV40-transformed rabbit cells using cell fusion and in situ hybridization.. Journal of General Virology 21:69–81
    [Google Scholar]
  15. Wicker R., Avrameas S. 1969; Localization of virus antigens by enzyme-labelled antibodies.. Journal of General Virology 4:465–471
    [Google Scholar]
  16. Zouzias D., Prasad I., Basilico C. 1977; State of the viral DNA in rat cells transformed by polyoma virus. II. Identification of the cells containing nonintegrated viral DNA and the effect of viral mutations.. Journal of Virology 24:142–150
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-41-1-201
Loading
/content/journal/jgv/10.1099/0022-1317-41-1-201
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error