1887

Abstract

Summary

5-Aminoacridine in concentrations which had little or no effect on growth rate of the host organisms greatly reduced the yield of phage from bacteria infected with phage . The acridine reduced the number of bacteria releasing infective phage, and also the number of particles/bacterium. The inhibitory activity of the acridine became apparent at or just before the appearance of the first phage particles. The length of the eclipse period or latent period was not affected. Since 5-aminoacridine inhibited the synthesis of infective DNA, this could account for the decreased yield of complete infective phage particles.

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1969-04-01
2021-10-19
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