1887

Abstract

Summary

Mice challenged with rabies virus were vaccinated 24 h later with one of two types of rabies vaccine. Vaccine prepared from a BHK cell substrate resulted in the production of serum interferon and neutralizing antibody, whereas vaccine prepared from a human diploid cell substrate gave rise to neutralizing antibody but no interferon. Only the first vaccine was effective in reducing mortality.

Various combinations of mouse hyperimmune antiserum, purified IgG, complement and RNase were administered to other groups of mice challenged with rabies, but these had no significant effect on their survival.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-36-1-51
1977-07-01
2019-10-15
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-36-1-51
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error