1887

Abstract

SUMMARY

Treatment of measles virus-infected cells with cycloheximide results in a three-fold increase of H-uridine incorporation into the 12 to 36S mRNA species and in the inhibition of genomic 50S RNA synthesis. Consistent with these observations was the finding of a build-up of polyribosomes but an absence of nucleocapsids in the infected cells. These results suggest that measles virus RNA replication, but not transcription, is dependent upon active protein synthesis.

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/content/journal/jgv/10.1099/0022-1317-35-3-579
1977-06-01
2022-01-19
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