1887

Abstract

Summary

Human papovavirus, RFV, isolated from urine of a renal transplant patient was compared with two strains of SV40 and with the prototype human papovavirus, BKV. Neutralization tests showed that RFV and BKV are indistinguishable, while large-plaque (LP) and small-plaque (SP) isolates of SV40 gave a low but significant level of cross-reaction with rabbit or human antisera against RFV.

DNA reassociation saturation tests using I-labelled RFV DNA show that BKV has 88% homology, and SP-SV40 has 29% homology to RFV. We conclude that RFV and BKV are nearly, if not totally, identical and are not SV40 variants.

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/content/journal/jgv/10.1099/0022-1317-35-1-67
1977-04-01
2019-11-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-35-1-67
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