1887

Abstract

SUMMARY

RNA extracted from cells previously stimulated to synthesize the antiviral protein, interferon, causes species-specific interferon synthesis when added to heterospecific cell cultures. Our results confirm the report of De Maeyer-Guignard, De Maeyer & Montagnier (1972). We have used this observation to obtain a relative quantitative assay for the interferon messenger RNA activity. At appropriate concentrations, the yield of interferon is proportional to the concentration of RNA adsorbed to recipient cell cultures.

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1975-05-01
2022-01-25
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