1887

Abstract

Summary

The response to various stimuli of herpes simplex virus-specified deoxypyrimidine kinase activity differs significantly from that of the thymidine kinase and deoxycytidine kinase of mammalian cells. However, the two phosphorylating activities of the HSV deoxypyrimidine kinase are themselves quite distinct in their biochemical behaviour.

It has been impossible to separate the HSV-coded thymidine and deoxycytidine phosphorylating activities by their sedimentation, electrophoretic or size characteristics. The evidence suggests that both deoxypyrimidine nucleosides are phosphorylated at the same active site.

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/content/journal/jgv/10.1099/0022-1317-24-3-481
1974-09-01
2019-10-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-24-3-481
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