1887

Abstract

SUMMARY

Virus-like particles have been found closely associated with the centrioles in CHO-K1 and CHO-10 cells but not in other cell lines. They are spherical and measure 55 to 65 nm in overall diam.; their central cores of about 35 to 40 nm diam. sometimes appear hollow and sometimes dense. An amorphous matrix similar to that surrounding the centrioles is found around the particles. The possibility that they represent a type-A virus is discussed.

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/content/journal/jgv/10.1099/0022-1317-24-2-395
1974-08-01
2022-01-17
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References

  1. Aaronson S. A., Todaro G., Scolnick E. M. 1971; Induction of murine C-type viruses from clonal lines of virus-free BALB/3T3 cells. Science, New York 174:157–159
    [Google Scholar]
  2. Bernhard W. 1973; Oncornaviruses. Type A and C virus particles in murine and other mammalian leukaemias and sarcomas. In Ultrastructure of Animal Viruses and Bacteriophage283–305 Edited by Dalton A. J., Hagenau F. New York and London: Academic Press;
    [Google Scholar]
  3. Lowy D. R., Rowe W. P., Teich N., Hartley J. W. 1971; Murine leukaemia virus: High-frequency activation in vitro by 5-iododeoxyuridine and 5-bromodeoxyuridine. Science, New York 174:155–156
    [Google Scholar]
  4. Tihon C., Green M. 1973; Cyclic AMP-amplified replication of RNA tumour virus-like particles in Chinese hamster ovary cells. Nature New Biology 244:227–231
    [Google Scholar]
  5. Tjio J. H., Puck T. T. 1958; Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture. Journal of Experimental Medicine 108:259–268
    [Google Scholar]
  6. Todaro G., Hsuebner R. J. 1972; The viral oncogene hypothesis: new evidence. Proceedings of the National Academy of Sciences of the United States of America 69:1009–1015
    [Google Scholar]
  7. Wheatley D. N. 1971; Cilia in cell-cultured fibroblasts. III. Relationship between mitotic activity and cilium frequency in mouse 3T6 fibroblasts. Journal of Anatomy (London), no 367–382
    [Google Scholar]
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