1887

Abstract

SUMMARY

U.v. irradiation of SH-RP cells, a lymphoblastoid cell line carrying Epstein–Barr virus, which was derived from a patient with acute myeloid leukaemia, retarded cell growth but significantly enhanced the percentage of cells containing virus-capsid antigen (VCA) as demonstrated by indirect immunofluorescence. The effects of u.v. irradiation on SH-RP cultures were reversible under normal conditions of medium replenishment every four days. Starving the cultures did not modify these effects.

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1973-10-01
2024-04-26
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References

  1. Baltus E. 1954; Observations sur le rôle biochimique du nucleole. Biochimica et biophysica acta 15:263–267
    [Google Scholar]
  2. De The G. B., Ambrosioni J. C., Ho H. C., Kwan H. C. 1969; Lymphoblastoid transformation and presence of herpes-type viral particles in Chinese nasopharyngeal tumour cultured in vitro. Nature, London 221:770–771
    [Google Scholar]
  3. Diehl V., Henle G., Henle W., Kohn G. 1968; Demonstration of a herpes group virus in cultures of peripheral leukocytes from patients with infectious mononucleosis. Journal of Virology 2:663–669
    [Google Scholar]
  4. Einhorn N., Klein G., Clifford P. 1970; Increase in antibody titre against the EBV-associated membrane antigen complex in Burkitt’s lymphoma and nasopharyngeal carcinoma after local irradiation. Cancer 26:1013–1021
    [Google Scholar]
  5. Einhorn N., Henle G., Henle W., Klein G., Clifford P. 1972; Effect of local radiotherapy on the antibody levels against EBV-induced early and capsid antigens (EA and YCA) in patients with certain malignant tumours. International Journal of Cancer 9:182–192
    [Google Scholar]
  6. Epstein M. A., Achong B. G. 1968; Specific immunofluorescence test for the Herpes-type E.B. virus of Burkitt’s lymphoblasts, authenticated by electron microscopy. Journal of the National Cancer Institute 40:593–607
    [Google Scholar]
  7. Epstein M. A., Achong B. G., Barr Y. M. 1964; Virus particles in cultured lymphoblasts from Burkitt’s lymphoma. Lancet 1:702–703
    [Google Scholar]
  8. Epstein M. A., Achong B. C., Pope J. H. 1967; Virus in cultured lymphoblasts from a New Guinea Burkitt lymphoma. British Medical Journal 2:290–291
    [Google Scholar]
  9. Epstein M. A., Barr Y. M., Achong B. O. 1964; A second virus-carrying tissue culture (EB-2) of lymphoblast from Burkitt’s lymphoma. Pathologie et Biologie (Semaine Hospital), Paris 12:1233–1234
    [Google Scholar]
  10. Errera M., Ficq A. 1955; Effects of ultraviolet light on the protein and nucleic acid metabolism of the different parts of the starfish oocyte. In Progress in Radiobiology pp 3–7 Edited by Mitchell S. J., Holmes B. E., Smith C. L. Edinburgh: Oliver and Boyd;
    [Google Scholar]
  11. Gerber P. 1972; Activation of ebv by 5-bromodeoxyuridine in ‘virus-free’ human cells. Proceedings of the National Academy of Sciences of the United States of America 69:83–85
    [Google Scholar]
  12. Gerber P., Monroe J. H. 1968; Studies of leukocytes growing in continuous culture derived from normal human donors. Journal of the National Cancer Institute 40:855–866
    [Google Scholar]
  13. Hampar B., Derge J. G., Martos L. M., Walker J. L. 1972; Synthesis of Epstein–Barr virus after activation of the viral genome in a ‘virus-negative’ human lymphoblastoid cell (Raji) made resistant to 5-bromo-deoxyuridine. Proceedings of the National Academy of Sciences of the United States of America 69:72–82
    [Google Scholar]
  14. Hampar B., Martos L. M., Walker J. L. 1971; Epstein–Barr virus in human lymphoblastoid cells: Enhancing the percentage of virus-positive cells by co-cultivation with African Green Monkey (Vero) cells. Journal of the National Cancer Institute 47:535–537
    [Google Scholar]
  15. Henle G., Henle W. 1966; Immunofluorescence in cells derived from Burkitt’s lymphoma. Journal of Bacteriology 91:1248–1256
    [Google Scholar]
  16. Henle W., Henle G. 1968; Effect of arginine-deficient media on the herpes-type virus associated with cultured Burkitt’s lymphoma cells. Journal of Virology 2:182–191
    [Google Scholar]
  17. Hinuma Y., Konn M., Yamaguchi J., Wudarski D. J., Blakeslee J. R. 1967; Immunofluorescence and Herpes-type particles in P3HR-1 Burkitt’s lymphoma cell line. Journal of Virology 1:1045–1051
    [Google Scholar]
  18. Hirschaut Y., Glade P., Moses H., Manaker R., Chessin L. 1969; Association of Herpes-like virus infection with infectious mononucleosis. American Journal of Medicine 47:520–527
    [Google Scholar]
  19. Lai P. K., Papadimitriou J. M., Kennett D., Mackay-Scollar E. M., Alpers M. P. 1973; A lymphoblastoid cell line derived from cells of myeloid leukaemia by infection with the Epstein–Barr herpesvirus. Cytobios (in the press)
    [Google Scholar]
  20. Lebedinsky A. V., Mastryukova V. M., Strzhizhovsky A. D. 1961; On the mechanism of inhibition of cell division induced by ionising radiation. In Symposium on Initial Effects of Ionising Radiation on Cells pp 211–222 Edited by Harris R. J. C. London: Academic Press;
    [Google Scholar]
  21. Lytle C. D. 1971; Host-cell reactivation in mammalian cells, 1. Survival of ultraviolet irradiated Herpes virus in different cell-lines. International Journal of Radiation Biology 19:329–337
    [Google Scholar]
  22. Maurer B. A., Glick J. L., Minowada J. 1970; DNA synthesis in E.B. virus-containing Burkitt lymphoma cultures during a temperature cycling procedure. Proceedings of the Society for Experimental Biology and Medicine 133:1026–1030
    [Google Scholar]
  23. Moore G. E., Grace J. T. Jun., Citron P., Gerner R. E., Burns A. 1966; Leukocyte cultures of patients with leukaemia and lymphomas. New York State Journal of Medicine 66:2757–2764
    [Google Scholar]
  24. Pope J. H. 1967; Establishment of a cell line from peripheral leucocytes in infectious mononucleosis. Nature, London 216:810–811
    [Google Scholar]
  25. Pope J. H. 1968; Establishment of a cell line from Australian leukaemic patients: presence of a Herpes-like virus. Australian Journal of Experimental Biology and Medical Science 46:643–645
    [Google Scholar]
  26. Roizman B. 1972; The biochemical features of herpesvirus-infected cells, particularly as they relate to their potential oncogenicity. In Oncogenesis and Herpesviruses pp 1–17 Edited by Biggs P. M., de-The G., Payne L. N. Lyon: International Agency for Research on Cancer;
    [Google Scholar]
  27. Sairenji T., Hinuma Y. 1971; Relationship between the synthesis of Epstein–Barr virus and growth of host cells in a Burkitt lymphoma cell line, P3HR-1. Japanese Cancer Association GANN Monograph 10:113–122
    [Google Scholar]
  28. Sugawara K., Mizuno F., Osato T. 1972; Epstein–Barr virus-associated antigens in non-producing clones of human lymphoblastoid cell lines. Nature New Biology 239:242–243
    [Google Scholar]
  29. Yata J., Klein G., Hewetson J., Gergely L. 1970; Effect of metabolic inhibitors on membrane immunofluorescence reactivity of established Burkitt lymphoma cell lines. International Journal of Cancer 5:394–403
    [Google Scholar]
  30. Zajac B. A., Kohn G. 1970; Epstein–Barr virus antigens, marker chromosome and interferon production in clones derived from cultured Burkitt tumour cells. Journal of the National Cancer Institute 45:399–406
    [Google Scholar]
  31. Zur Hausen H., Schulte-Holthausen H. 1970; Presence of EBV nucleic acid homology in a ‘virus free’ line of Burkitt’s lymphoma cells. Nature, London 227:245–248
    [Google Scholar]
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