1887

Abstract

Summary

Established (laboratory) strains and fresh isolates of herpes simplex virus from patients with skin and genital lesions were classified into four groups depending on their effects on the social interaction among infected p-2 cells. The groups comprised strains causing (1) rounding of cells but no adhesion or fusion, (2) loose aggregation of rounded cells, (3) tight adhesion of rounded cells, and (4) fusion of cells into polykaryocytes. Protype strains from each group were found to differ with respect to immunologic specificity, buoyant density in CsCl solutions and stability at 4°.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-2-3-357
1968-05-01
2022-05-22
Loading full text...

Full text loading...

/deliver/fulltext/jgv/2/3/JV0020030357.html?itemId=/content/journal/jgv/10.1099/0022-1317-2-3-357&mimeType=html&fmt=ahah

References

  1. Dowdle W. R., Nahmias A. J., Harwell R. W., Pauls F. P. 1967; Association of antigenic type of herpesvirus hominis with site of viral recovery. J. Immun in the Press
    [Google Scholar]
  2. Eagle H. 1959; Amino add metabolism in mammalian cell cultures. Science; N.Y: 130432
    [Google Scholar]
  3. Epstein M. A. 1962; Observations on the mode of release of herpes virus from infected HeLa cells. J. Cell Biol 12:589
    [Google Scholar]
  4. Gray A., Tokumaru T., Scott T. F. 1958; Different cytopathogenic effects observed in HeLa cells infected with herpes simplex virus. Arch. ges. Virusforsch 8:60
    [Google Scholar]
  5. Hinze H. C., Walker D. L. 1961; Variation of herpes simplex virus in persistently infected tissue cultures. J. Bad 82:498
    [Google Scholar]
  6. Hoggan M. D., Roizman B. 1959; The isolation and properties of a variant of herpes simplex producing multinucleated giant cells in monolayer cultures in the presence of antibody. Am. J. Hyg 70:208
    [Google Scholar]
  7. Hoggan M. D., Roizman B., Turner T. B. 1960; The isolation and properties of a variant of herpes simplex producing multinucleated giant cells in monolayer cultures in the presence of antibody. Am. J. Hyg 84:152
    [Google Scholar]
  8. Kohlhage H. 1964; Differenzierung von Plaquevarianten des Herpes simplex Virus durch Gradientenzentrifugation und Säulenchromatographie. Arch. ges. Virusforsch 14:358
    [Google Scholar]
  9. Kohlhage H., Siegert R. 1962; Zwei genetisch determinierte Varianten eines Herpes Simplex Stammes. Arch. ges. Virusforsch 12:273
    [Google Scholar]
  10. Munk K., Donner D. 1963; Cytopathischer Effekt und Plaque-morphologie verschiedener Herpes Simplex Virus Stämme. Arch. ges. Virusforsch 13:529
    [Google Scholar]
  11. Nu S., Kamahora J. 1961; Cytopathic changes induced by herpes simplex virus. Bikern J 4:255
    [Google Scholar]
  12. Plummer G. 1964; Serological comparison of the herpes viruses. Br. d. exp. Path 45:135
    [Google Scholar]
  13. Roane P. R., Roizman B. 1964; Studies of determinant antigens of viable cells. II. Demonstration of altered antigenic reactivity of HEp-2 cells infected with herpes simplex virus. Virology 22:1
    [Google Scholar]
  14. Roizman B., Aurelian L. 1965; Abortive infection of canine cells by herpes simplex virus. I. Characterization of viral progeny from cooperative infection with mutants differing in ability to multiply in canine cells. J. molec. Biol 11:528
    [Google Scholar]
  15. Roizman B., Roane P. R. 1961; A physical difference between two strains of herpes simplex virus apparent on sedimentation in cesium chloride. Virology 15:75
    [Google Scholar]
  16. Roizman B., Roane P. R. 1963; Demonstration of a surface difference between virions of two strains of herpes simplex virus. Virology 19:198
    [Google Scholar]
  17. Roizman B., Spring S. B. 1967; Alteration in immunologic specificity of cells infected with cytolytic viruses. Transplantation in the Press
    [Google Scholar]
  18. Schneweiss E. K. 1962a; Der cytopathischeEffekt des herpes simplex virus. Zbl. Bakt. ParasitKde Orig 186:467
    [Google Scholar]
  19. Schneweiss E. K. 1962b; Serologische Untersuchungen zur Typendifferenzierung des Herpes virus Hominis. Z. ImmunForsch. exp. Ther 124:24
    [Google Scholar]
  20. Spear P. G., Roizman B. 1967; The buoyant density of herpes simplex virus in CsCl solutions. Nature; Lond: 214713
    [Google Scholar]
  21. Spring S. B., Roizman B. 1967; Studies of herpes simplex virus products in productive and abortive infection. I. Stabilization of formaldehyde and preliminary analyses by isopycnic centrifugation in CsCl. J. Virol 1:294
    [Google Scholar]
  22. Watson D. H., Wdldy P. 1963; Some serological properties of herpes virus particles studied with electron microscope. Virology 21:100
    [Google Scholar]
  23. Wheeler C. E. 1964; Biologic comparison of a syncytial and a small giant cell-forming strain of herpes simplex. J. Immun 93:749
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-2-3-357
Loading
/content/journal/jgv/10.1099/0022-1317-2-3-357
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error